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MP57-13 AGE-STRATIFIED POTENCY OUTCOMES OF BILATERAL NERVE SPARING ROBOTIC-ASSISTED RADICAL PROSTATECTOMY

2021· article· en· W3188308256 on OpenAlexaboutno aff
Adel Arezki, Iman Sadri, Ahmed S. Zakaria, Félix Couture, David‐Dan Nguyen, Pierre I. Karakiewicz, Dean Elterman, Kevin C. Zorn

Bibliographic record

VenueThe Journal of Urology · 2021
Typearticle
Languageen
FieldMedicine
TopicProstate Cancer Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineProstatectomyAndrogen deprivation therapyProstate cancerPotencySexual functionGeneral surgerySurgeryInternal medicineCancer

Abstract

fetched live from OpenAlex

advancements have led to decreased rates of infectious complications.The AUA best practice statement recommends administering perioperative aminoglycoside with either vancomycin or a first or second generation cephalosporin.There is a lack of evidence to show which antibiotic combinations correlate to decreased rates of post-operative infection.This study aims to determine adherence to AUA guidelines and which antibiotics combinations are associated with decreased rates of infection.METHODS: The Truven MarketScan (MS) database of commercial claims encounters was used to identify men over age 18 who underwent penile prosthetic surgery between 2012 and 2017.Antibiotic combinations were generated to stratify patients and determine risk of post-operative infection (Table 1).A cox proportional hazards model was performed from time of penile prosthetic surgery to date of infection.Binary cofactors were used for each antibiotic combination.Men were considered censored at the time they dropped out of MS.RESULTS: 17,067 men underwent penile prosthetic surgery.Of those, 6889 had documented antibiotics administered on the day of surgery.Those who did not have an antibiotic record were excluded.49% of patients were administered antibiotics according to AUA guidelines.The remainder of patients received either a single antibiotic or another combination.There was no difference in post-operative infection rates between patients who received an AUA recommended antibiotic combination and other antibiotics (Table 2).CONCLUSIONS: Approximately half of men undergoing penile prosthetic surgery were administered antibiotics according to AUA guidelines.There was no difference in infection rates post-operatively, regardless of which antibiotic combination administered.Perioperative antibiotic use varies widely and surgeons should tailor their antibiotics regiment based on local antibiogram.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.134
Threshold uncertainty score0.266

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0030.005
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.289
Teacher spread0.259 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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