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Record W3189995579

Phylogenetic trees of mutant Staphylococcus aureus produce recombinant thrombolytic enzyme

2021· article· en· W3189995579 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMicrobial Metabolism and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsStaphylococcus aureusBiologyGeneMutantPhylogenetic treeGeneticsAccession number (library science)Strain (injury)MicrobiologyGenBankBacteria
DOInot available

Abstract

fetched live from OpenAlex

The aim of study make Phylogenetic trees of mutant Staphylococcus aureus produce recombinant thrombolytic enzyme. Isolation S.aureus from different clinical sources from human that identified  by vitek2-GP :  280 (56%) tonsils , 100 (20%) nose, 40 (8%) tumors, 17 (3.4%) urine, 27 (5.4%) skin(Acne) and 36 (7.2%) Blood. Genotypic analysis of sak gene showed presence of sak gene in  all mutant VSSA and MSSA S.aureus after done chemical mutagenesis compared with control before chemical mutagenesis, size  of sak gene (492bp) compared with DNA Ladder (1500bp).DNA Sequencing of  S.aureus elucidate the coding region for Sak gene amplified from mutant VSSA and MSSA compared with analogous sequence of the same gene from standard strain of S.aureus possessed in  BLAST / NCBI on the web site. Register strain in NCBI(National Center of Biotechnology Institute) Strain carry ID in NCBI/Gene Bank : strain1 ID=MN907801.1,strain2 ID=MN907802.1, strain3 ID=MN907803.1, strain4 ID=MN907804.1, strain5 ID=MN907805.1 and strain6 ID=MN907806.1; convert nucleotide sequence to protein by using Mega 6 program software. Phylogenetic trees drawn by neighbor-joining trees of strain based on spa-X Gene sequences for all strain that recording in NCBI/GeneBank  hold accession number MN907801.1, MN907802.1, MN907803.1, MN907804.1, MN907805.1, MN9078026.1 Staphylococcus aureus IRAQ, the relativity  between strain 0.9893-1.5814(99%); the relativity between 6 strain with strain in Australia 1.916(100%) 12/ CP043389.1:209416-2095276 Staphylococcus aureus Australia Meliboume; the relativity with strain 8 USA:KY America (100%), also the relativity with strain19 (100%) CP020960.1:153230:953990 Staphylococcus aureus Canada: Calgary (100%) relativity with strain(12,13,14,15,16,17,21,18), this results relativity with other strain in the world.The relativity of IRAQ strain between strain MN907801.1 with strain MN907804.1 0.8960(100%); the relativity between MN907804.1 with strain MN907805.1 is 0.9000(99%); the  relativity between strain MN907801.1 and MN907805.1 is 0.3175(99%); the relativity of strain MN907801.1 with (relativity between MN907806.1, MN907805.1, MN907804.1, MN907801.1 is (99%)) 0.3038 (99%); the  relativity between MN907803. (relativity between all strain) 0.2933(99%) and shown link in NCBI/GeneBank for strain recording with number  060753351. Compatibility IRAQ strain with other strain in the world is  99% in  France, Japan, China(Zhejiang) province, USA (New York city),Ghana: Accra, Japan:Kyoto, Australia:Melbourne, USA:Detroit, USA:VA, China, USA:California, Canada:Calgary, USA, USA:SanDiego, Canada: Calgary.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.035
Threshold uncertainty score0.476

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.243
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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