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Record W3190511974 · doi:10.1002/9780471420194.tnmm32

Lymphoma

2017· other· en· W3190511974 on OpenAlexaff
Richard Tsang, Michael Crump

Bibliographic record

VenueTNM Online · 2017
Typeother
Languageen
FieldMedicine
TopicLymphoma Diagnosis and Treatment
Canadian institutionsPrincess Margaret Cancer CentreUniversity of Toronto
Fundersnot available
KeywordsMedicineLymphomaImmunosuppressionChemotherapyHistologyWorking FormulationBone marrowStage (stratigraphy)PathologyNon-Hodgkin's lymphomaInternal medicine

Abstract

fetched live from OpenAlex

Summary Hodgkin lymphoma is the classical type, with a small proportion of nodular lymphocyte‐predominant histology, and usually presents at a localized stage. Non‐Hodgkin lymphoma has many subtypes, but most are of B‐cell origin, and can broadly be divided between aggressive and indolent histologies for treatment purposes. There is large geographical variation between the individual subtypes of non‐Hodgkin lymphoma and varying aetiological agents (e.g. Epstein‐Barr virus or Helicobacter pylori) or predisposing factors (e.g. immunosuppression or autoimmune diseases). Symptoms include lymphadenopathy, mass lesion in organs and sometimes, constitutional symptoms such as weight loss, fever and night sweats. Standard investigations are CT neck, chest, abdomen and pelvis, FDG‐PET scan, complete blood count and blood work for organ function, HIV status, hepatitis serology and bone marrow biopsy. Early‐stage Hodgkin lymphoma is treated with combined brief chemotherapy and radiation therapy with a high cure rate. Advanced‐stage Hodgkin lymphoma are treated with full courses of chemotherapy with a good cure rate. Non‐Hodgkin lymphomas of aggressive histology are primarily treated with chemotherapy with a moderately high cure rate. Non‐Hodgkin lymphomas of indolent histology usually present in advanced stages and are not curable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.116
Threshold uncertainty score0.000

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.1160.052

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.321
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2017
Admission routes1
Has abstractyes

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