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Record W3191809422 · doi:10.1016/j.cell.2021.08.017

The origins of SARS-CoV-2: A critical review

2021· review· en· W3191809422 on OpenAlexafffund
Edward C. Holmes, Stephen A. Goldstein, Angela L. Rasmussen, David L. Robertson, Alexander Crits‐Christoph, Joel O. Wertheim, Simon J. Anthony, William Barclay, Maciej F. Boni, Peter C. Doherty, Jeremy Farrar, Jemma L. Geoghegan, Xiaowei Jiang, Julian L. Leibowitz, Stuart J. D. Neil, Tim Skern, Susan R. Weiss, Michael Worobey, Kristian G. Andersen, Robert F. Garry, Andrew Rambaut

Bibliographic record

VenueCell · 2021
Typereview
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsUniversity of Saskatchewan
FundersNational Institute of Allergy and Infectious DiseasesMedical Research CouncilFudan UniversityBiotechnology and Biological Sciences Research CouncilBill and Melinda Gates FoundationAustrian Science FundCenters for Disease Control and PreventionUniversity of PennsylvaniaCanada Foundation for InnovationEuropean and Developing Countries Clinical Trials PartnershipArizona Board of RegentsAustralian Research CouncilCoalition for Epidemic Preparedness InnovationsNational Center for Advancing Translational SciencesNational Human Genome Research InstituteWellcome TrustNational Institutes of HealthMinistry of Agriculture of the People's Republic of ChinaNational Science Foundation
KeywordsBiologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)CoronavirusBetacoronavirusSars virusVirologyCoronavirus InfectionsPopulationPandemicEnvironmental healthOutbreakDiseasePathologyMedicineInfectious disease (medical specialty)

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.876
Threshold uncertainty score0.834

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.175
GPT teacher head0.468
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations512
Published2021
Admission routes2
Has abstractyes

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