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Record W3193323274 · doi:10.14351/0831-4985-34.1.32

Comparing Methods of Determining Formalin Concentration in Fluid Preservatives

2020· article· en· W3193323274 on OpenAlexaffvenue
Irene Finkelde, Robert Waller

Bibliographic record

VenueCollection Forum · 2020
Typearticle
Languageen
FieldEnvironmental Science
TopicIndoor Air Quality and Microbial Exposure
Canadian institutionsCanadian Museum of NatureQueen's University
Fundersnot available
KeywordsPreservativeFormaldehydeTitrationChemistryChromatographySulfiteFixativePipetteSodium sulfiteAqueous solutionSodiumBiochemistryFood scienceOrganic chemistry

Abstract

fetched live from OpenAlex

Abstract Formalin (3.7% weight/weight [w/w], 4% weight/volume [w/v] aqueous formaldehyde) is commonly used as a fixative to prevent postmortem changes in the tissues of a specimen. The specimen is then either maintained in formalin or transferred to another fluid preservative, such as ethanol or isopropanol, for long-term preservation. Residual formalin often remains in the preservation fluid. As formaldehyde is a known carcinogen, it is important to know the concentration present in preservation fluids. A titration method has been developed to determine formalin concentration in fluid preservatives. It utilizes sodium sulfite to react with formaldehyde in solution. An adjustable, repeating pipette and a digital titrator allow for the rapid determination of formalin concentrations in small samples (<1 ml). This method of titration is compared with three commercially available methods of determining formaldehyde and formalin concentration: two brands of formaldehyde test strips, Quantofix® (Machery-Nagel GmbH) and MQuant® (EMD Millipore Corp), and a drop count titration test kit (Hach® formaldehyde test kit, model FM-1). A comparison and evaluation are made on the effectiveness of each method in determining the concentration of formalin in preservation fluids.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.018
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.054

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.018
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.002
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0020.002
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.050
GPT teacher head0.304
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2020
Admission routes2
Has abstractyes

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