A CASE REPORT AND LITERATURE REVIEW: METACHRONOUS TUMOUR IN SINGLE PATIENT (CARCINOMA CERVIX AND CARCINOMA LUNG)
Bibliographic record
Abstract
INTRODUCTION: - Multiple primary tumors can be synchronous when detected simultaneously (or) metachronous when detected after a variable time interval. Association of two cancer in same patient is unusual but has been widely reported in the literature. CASE PRESENTAION: - A 55-year-old women was diagnosed in December 2018 as squamous cell carcinoma cervix FIGO STAGE IIIB & she received denitive chemoradiation 46GY/23# for 5 weeks with 5 cycles weekly injection carboplatin under AUC 2 followed by Brachytherapy and completed treatment in February 2019. She was on regular follow up till December 2020. Later she presented with upper back pain. She was evaluated for the same. CT Thorax suggestive of right upper lobe lung mass and PET- CT S/O Right Lung mass lesion with extension into spinal rd th canal & lytic destruction of D2/D3 Vertebrae and Right 3 , 4 rib. CT guided Biopsy s/o squamous cell carcinoma with IHC- p16 & p40-Positive, nd TTF-Negative and diagnosed as 2 primary carcinoma lung Stage IV. She received 6 cycles systemic chemotherapy completed in May 2021. She improved clinically & radiologically with systemic chemotherapy paclitaxel & carboplatin. CONCLUSION: - Metachronous tumor in single patient is unusual & management depends on stage of presentation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".