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Record W3196048708 · doi:10.1016/j.jdin.2021.06.006

Identifying gaps and providing recommendations to address shortcomings in the investigation of acne sequelae by the Personalising Acne: Consensus of Experts panel

2021· article· en· W3196048708 on OpenAlexaff
Alison Layton, Andrew Alexis, Hilary Baldwin, Stefan Beissert, Vincenzo Bettoli, J.Q. Del Rosso, Brigitte Dréno, Linda Stein Gold, Julie Harper, Charles Lynde, Diane Thiboutot, Jonathan S. Weiss, Jerry Tan

Bibliographic record

VenueJAAD International · 2021
Typearticle
Languageen
FieldMedicine
TopicAcne and Rosacea Treatments and Effects
Canadian institutionsWestern UniversityWindsor Clinical ResearchLynde Centre for DermatologyUniversity of Toronto
FundersGalderma
KeywordsAcneMedicineDelphi methodExpert opinionMEDLINEGuidelineQuality of life (healthcare)DermatologyIntensive care medicineNursingPathologyComputer science

Abstract

fetched live from OpenAlex

BACKGROUND: The physical sequelae of acne include erythema, hyperpigmentation, and scarring, which are highly burdensome for patients. Early, effective treatment can potentially limit and prevent sequelae development, but there is a need for guidance for and evidence of prevention-oriented management to improve patient outcomes. OBJECTIVE: To identify unmet needs of acne sequelae and generate expert recommendations to address gaps in clinical guidance. METHODS: The Personalizing Acne: Consensus of Experts panel of 13 dermatologists used a modified Delphi approach to achieve a consensus on the clinical aspects of acne sequelae. A consensus was defined as ≥75% of the dermatologists voting "agree" or "strongly agree." All voting was electronic and blinded. RESULTS: The panel identified gaps in current guidance and made recommendations related to acne sequelae. These included identification and classification of sequelae, pertinent points to consider for patient consultations, and management aimed at reducing the development of sequelae. LIMITATIONS: The recommendations are based on expert opinion and made in the absence of high-quality evidence. CONCLUSIONS: The identified gaps should help inform future research and guideline development for acne sequelae. The consensus-based recommendations should also support the process of consultations throughout the patient journey, helping to reduce the development and burden of acne sequelae through improved risk factor recognition, early discussion, and appropriate management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.248
metaresearch head score (Gemma)0.363
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.248
Threshold uncertainty score0.928

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2480.363
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0030.006
Bibliometrics0.0080.004
Science and technology studies0.0050.003
Scholarly communication0.0080.008
Open science0.0070.011
Research integrity0.0150.013
Insufficient payload (model declined to judge)0.0060.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.087
GPT teacher head0.354
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations21
Published2021
Admission routes1
Has abstractyes

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