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Reporting transparency and completeness in trials: Paper 3 – trials conducted using administrative databases do not adequately report elements related to use of databases

2021· review· en· W3199432622 on OpenAlexaffabout
Mahrukh Imran, Kimberly Mc Cord, Stephen J. McCall, Linda Kwakkenbos, Margaret Sampson, Ole Fröbert, Chris Gale, Lars G. Hemkens, Sinéad Langan, David Moher, Clare Relton, Merrick Zwarenstein, Edmund Juszczak, Brett D. Thombs

Bibliographic record

VenueJournal of Clinical Epidemiology · 2021
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcGill UniversityChildren's Hospital of Eastern OntarioInstitute for Clinical Evaluative SciencesWestern UniversityOttawa HospitalJewish General Hospital
FundersSteno Diabetes Center AarhusMedical Research CouncilNational Institute for Health and Care ResearchWellcome Trust
KeywordsConsolidated Standards of Reporting TrialsMedicineClinical trialMEDLINEDatabaseTransparency (behavior)Data extractionFamily medicineCochrane LibraryRandomized controlled trialResearch designComputer scienceStatisticsSurgeryInternal medicine

Abstract

fetched live from OpenAlex

OBJECTIVE: We evaluated reporting completeness and transparency in randomized controlled trials (RCTs) conducted using administrative data based on 2021 CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data (CONSORT-ROUTINE) criteria. STUDY DESIGN AND SETTING: MEDLINE and the Cochrane Methodology Register were searched (2011 and 2018). Eligible RCTs used administrative databases for identifying eligible participants or collecting outcomes. We evaluated reporting based on CONSORT-ROUTINE, which modified eight items from CONSORT 2010 and added five new items. RESULTS: Of 33 included trials (76% used administrative databases for outcomes, 3% for identifying participants, 21% both), most were conducted in the United States (55%), Canada (18%), or the United Kingdom (12%). Of eight items modified in the extension; six were adequately reported in a majority (>50%) of trials. For the CONSORT-ROUTINE modification portion of those items, three items were reported adequately in >50% of trials, two in <50%, two only applied to some trials, and one only had wording modifications and was not evaluated. For five new items, four that address use of routine data in trials were reported inadequately in most trials. CONCLUSION: How administrative data are used in trials is often sub-optimally reported. CONSORT-ROUTINE uptake may improve reporting.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.732
metaresearch head score (Gemma)0.903
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.268
Threshold uncertainty score0.331

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.7320.903
Meta-epidemiology (narrow)0.0030.004
Meta-epidemiology (broad)0.0070.014
Bibliometrics0.0120.018
Science and technology studies0.0040.010
Scholarly communication0.0180.016
Open science0.0060.011
Research integrity0.0070.007
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.994
GPT teacher head0.787
Teacher spread0.208 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designObservational
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2021
Admission routes2
Has abstractyes

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