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Record W3199713736 · doi:10.1002/jgc4.1502

Genetic counseling research and COVID‐19: A lesson in resiliency

2021· article· en· W3199713736 on OpenAlexafffundabout
Kennedy Borle, Alivia Dey, Prescilla Carrion, Jehannine Austin, Alison M. Elliott

Bibliographic record

VenueJournal of Genetic Counseling · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Rare Diseases
Canadian institutionsBC Children's HospitalProvincial Health Services AuthorityWomen's Health Research InstituteUniversity of British Columbia
FundersUniversity of British ColumbiaProvincial Health Services AuthorityGenome British ColumbiaBC Children's HospitalChildren's Hospital FoundationCanadian Institutes of Health ResearchGenome CanadaMcGill University
KeywordsGenetic counselingPandemicTranslational researchMedical educationPublic healthExome sequencingMedicineCoronavirus disease 2019 (COVID-19)PsychologyNursingGeneticsBiology

Abstract

fetched live from OpenAlex

GenCOUNSEL is the largest genetic counseling research grant awarded to date and brings together experts in genetic counseling, genomics, law and policy, health services implementation, and health economics research. It is the first project of its kind to examine the genetic counseling issues associated with the clinical implementation of genome-wide sequencing (exome and genome sequencing). GenCOUNSEL is a Canadian-based, multi-method research study that takes place over a variety of sites, including non-clinical, clinical, and laboratory research sites and includes the training of undergraduate and graduate students. The COVID-19 pandemic will likely have a lasting impact on genetic counseling service delivery, research, and training. Almost every aspect of the GenCOUNSEL research project has been impacted by the COVID-19 pandemic. Here we describe how our research recruitment strategies, methods, resource allocation, and training capacity have been affected. We discuss ways that we have adapted to the pandemic including revision of our research methods and work to understand the barriers in order to optimize opportunities. We finish with take-home messages to fellow researchers highlighting the importance of resiliency in genetic counseling research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.147
metaresearch head score (Gemma)0.169
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.147
Threshold uncertainty score0.775

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1470.169
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0170.028
Scholarly communication0.0170.023
Open science0.0050.021
Research integrity0.0140.029
Insufficient payload (model declined to judge)0.0180.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.334
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes3
Has abstractyes

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