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Structure-based classification of tauopathies

2021· article· en· 919 citations· W3202815206 on OpenAlex· 10.1038/s41586-021-03911-7

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.020
GPT teacher head0.330
Teacher spread
0.309 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Alzheimer's disease research and treatments
Field
Medicine
Canadian institutions
University of Toronto
Funders
National Institute on AgingRossy FoundationReta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology,University College LondonNational Center of Neurology and PsychiatryNational Institutes of HealthUniversity of CambridgeMedical Research CouncilEuropean Federation of Pharmaceutical Industries and AssociationsBiotechnology and Biological Sciences Research CouncilSchool of Medicine, Indiana UniversityNational Institute of Neurological Disorders and StrokeNational Institute for Health and Care ResearchDiamond Light SourceWellcome TrustJapan Agency for Medical Research and Development
Keywords
TauopathyCorticobasal degenerationProgressive supranuclear palsyTau proteinNeuropathologyTangleNeuroscienceBiologyPathologyAlzheimer's diseaseMedicineNeurodegenerationDisease
Has abstract in OpenAlex
no