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Using self-supervised feature learning to improve the use of pulse oximeter signals to predict paediatric hospitalization

2021· preprint· en· W3202889383 on OpenAlexaff
Paul Mwaniki, Timothy Kamanu, Samuel Akech, Dustin Dunsmuir, J. Mark Ansermino, M. J. C. Eijkemans

Bibliographic record

VenueWellcome Open Research · 2021
Typepreprint
Languageen
FieldEngineering
TopicNon-Invasive Vital Sign Monitoring
Canadian institutionsUniversity of British ColumbiaBC Children's Hospital
FundersAlliance for Accelerating Excellence in Science in AfricaAfrican Academy of SciencesNew Partnership for Africa's DevelopmentGovernment of the United KingdomWellcome Trust
KeywordsArtificial intelligenceDeep learningMachine learningComputer scienceInitializationLogistic regressionFeature (linguistics)Supervised learningPattern recognition (psychology)Feature engineeringFeature extractionArtificial neural network

Abstract

fetched live from OpenAlex

Background: The success of many machine learning applications depends on knowledge about the relationship between the input data and the task of interest (output), hindering the application of machine learning to novel tasks. End-to-end deep learning, which does not require intermediate feature engineering, has been recommended to overcome this challenge but end-to-end deep learning models require large labelled training data sets often unavailable in many medical applications. In this study, we trained machine learning models to predict paediatric hospitalization given raw photoplethysmography (PPG) signals obtained from a pulse oximeter. We trained self-supervised learning (SSL) for automatic feature extraction from PPG signals and assessed the utility of SSL in initializing end-to-end deep learning models trained on a small labelled data set with the aim of predicting paediatric hospitalization. Methods : We compared logistic regression models fitted using features extracted using SSL with end-to-end deep learning models initialized either randomly or using weights from the SSL model. We also compared the performance of SSL models trained on labelled data alone (n=1,031) with SSL trained using both labelled and unlabelled signals (n=7,578). Results : The SSL model trained on both labelled and unlabelled PPG signals produced features that were more predictive of hospitalization compared to the SSL model trained on labelled PPG only (AUC of logistic regression model: 0.78 vs 0.74). The end-to-end deep learning model had an AUC of 0.80 when initialized using the SSL model trained on all PPG signals, 0.77 when initialized using SSL trained on labelled data only, and 0.73 when initialized randomly. Conclusions : This study shows that SSL can improve the classification of PPG signals by either extracting features required by logistic regression models or initializing end-to-end deep learning models. Furthermore, SSL can leverage larger unlabelled data sets to improve performance of models fitted using small labelled data sets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.010
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.111
GPT teacher head0.339
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2021
Admission routes1
Has abstractyes

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