Serotonin Receptor (<scp><i>HTR2A</i></scp>) Gene Polymorphism Modulates Social Sharing of Happiness in Both American and Japanese Adults
Why this work is in the frame
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Bibliographic record
Abstract
Abstract A single nucleotide polymorphism in the serotonin 2A receptor gene ( HTR2A rs6311 guanine [G] vs. adenine [A]) appears associated with positive emotional contagion (social sharing of happiness) in Japanese people. However, it remains unknown whether the HTR2A polymorphism also impacts the social sharing of happiness in Western cultures. The present study thus compared 207 Japanese university students and 200 American adults (including non‐students). Social sharing of happiness was examined using a vignette‐based questionnaire. Participants were asked to imagine that they were experiencing an emotionally neutral event. At the same time, they were asked to imagine that a friend was experiencing a positive valence event (presence condition), whereas in the other condition such information was not presented (absence condition). Results showed that the G allele carriers felt happier in the presence than in the absence of the friend compared with participants with the AA genotype. Although we did not specifically consider comparability between the two samples, the findings suggest that the effect of HTR2A polymorphisms on social sharing of happiness observed in Japanese populations may be applicable to American populations.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it