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Record W3207910753 · doi:10.1111/jar.12949

Prevalence of diabetes in people with intellectual disabilities and age‐ and gender‐matched controls: A meta‐analysis

2021· review· en· W3207910753 on OpenAlex
Davy Vancampfort, Felipe Barreto Schuch, Tine Van Damme, Joseph Firth, Shuichi Suetani, Brendon Stubbs, Debbie Van Biesen

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Applied Research in Intellectual Disabilities · 2021
Typereview
Languageen
FieldMedicine
TopicDown syndrome and intellectual disability research
Canadian institutionsnot available
FundersNational Institute for Health and Care ResearchMedical Research Council CanadaSouth London and Maudsley NHS Foundation Trust
KeywordsMedicineOdds ratioMeta-analysisDiabetes mellitusDepression (economics)Internal medicineAnxietyPopulationCINAHLGerontologyDemographyPsychiatryPsychological interventionEndocrinologyEnvironmental health

Abstract

fetched live from OpenAlex

Abstract Background This meta‐analysis aims to: (i) describe the pooled prevalence of diabetes in people with intellectual disabilities, (ii) investigate the association with demographic, clinical and treatment‐related factors and (iii) compare the prevalence versus age‐ and gender‐matched general population controls. Methods Pubmed, Embase and CINAHL were searched until 01 May 2021. Random effects meta‐analysis and an odds ratio analysis were conducted to compare rates with controls. Results The trim‐ and fill‐adjusted pooled diabetes prevalence amongst 55,548 individuals with intellectual disabilities ( N studies = 33) was 8.5% (95% CI = 7.2%–10.0%). The trim‐ and fill‐adjusted odds for diabetes was 2.46 times higher (95% CI = 1.89–3.21) ( n = 42,684) versus controls ( n = 4,177,550). Older age ( R 2 = .83, p < .001), smoking (R 2 = .30, p = .009) and co‐morbid depression ( R 2 = .18, p = .04), anxiety ( R 2 = .97, p < .001), and hypertension ( R 2 = 0.29, p < .001) were associated with higher diabetes prevalence rates. Conclusions Our findings demonstrate that people with intellectual disabilities are at an increased risk of diabetes, and therefore routine screening and multidisciplinary management of diabetes is needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.041
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Science and technology studies, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.359
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.041
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0100.002
Bibliometrics0.0040.005
Science and technology studies0.0000.006
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.004
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.246
GPT teacher head0.426
Teacher spread0.180 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it