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Record W3208701992 · doi:10.5281/zenodo.3241794

Impacts of food contact chemicals on human health: scientific consensus statement

2019· article· en· W3208701992 on OpenAlex
Jane Muncke, Anna‐Maria Andersson, Thomas Backhaus, Justin M. Boucher, Bethanie Carney Almroth, Arturo Castillo Castillo, Jonathan Chevrier, Barbara Demeneix, Jean‐Baptiste Fini, David Gee, Birgit Geueke, Ksenia J. Groh, Jerry Heindel, Jane Houlihan, Christopher D. Kassotis, Carol F. Kwiatkowski, Lisa L. Lefferts, Olwenn Martin, Maricel V. Maffini, John Peterson Myers, Ángel Nadal, Cristina Nerı́n, Katherine E. Pelch, Seth Rojello Fernández, Robert M. Sargis, Ana M. Soto, Laura N. Vandenberg, Martin Wagner, Changqing Wu, R. Thomas Zoeller, Martin Scheringer

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueZenodo (CERN European Organization for Nuclear Research) · 2019
Typearticle
Languageen
FieldChemistry
TopicDye analysis and toxicity
Canadian institutionsMcGill University
Fundersnot available
KeywordsStatement (logic)Scientific consensusHuman healthScientific evidenceFood contact materialsBusinessEnvironmental healthPolitical scienceMedicineFood scienceFood packagingChemistryBiologyClimate changeEpistemologyEcologyPhilosophyLaw

Abstract

fetched live from OpenAlex

This is a preprint of a manuscript "Impacts of food contact chemicals on human health: scientific consensus statement," submitted to <em>Environmental Health</em> on June 7, 2019. Abstract Food packaging, as the most eminent type of food contact article, is of high societal use because it conserves and protects food, makes food transportable and conveys important information to consumers. It is also very relevant for marketing, which is of economic significance. Other types of food contact articles, such as storage containers, processing equipment and filling lines, are also important for modern food production and food supply. Food contact articles are made up of one or multiple different food contact materials and consist of food contact chemicals. Food contact chemicals transfer from all types of food contact materials and articles into food and, consequently, into humans. Here we summarize the scientific data and findings showing that food contact materials and articles are a relevant exposure pathway for known hazardous substances as well as for a plethora of toxicologically uncharacterized chemicals, both intentionally and non-intentionally added in food packaging. We describe areas of certainty, like the fact that chemicals migrate from food contact articles into food, and uncertainty, for example concerning the presence of unidentified migrating chemicals. In addition, we provide recommendations for research and policy, for example the testing of finished food packaging for chemical hazards. Our aim is to support science-based decision making in the interest of improving public health. Notably, reducing exposure to hazardous food contact chemicals contributes to the prevention of associated chronic diseases in the human population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.598
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0310.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.303
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it