What is the effect of preterm birth on permanent tooth crown dimensions? A systematic review and meta-analysis
Bibliographic record
Abstract
BACKGROUND: The permanent tooth formation process may be disrupted in preterm infants with potential discrepancies in size and subsequent occlusal disturbances. OBJECTIVE: To systematically analyse and quantitively synthesize the available evidence regarding the impact of preterm birth on permanent tooth crown dimensions. SEARCH METHODS: Unrestricted searches in 6 databases and manual searching of the reference lists in relevant studies were performed up to March 2021 (Medline via PubMed, CENTRAL, Cochrane Database of Systematic Reviews, Scopus, Web of Science, ProQuest Dissertations and Theses Global). SELECTION CRITERIA: Observational studies investigating permanent tooth crown dimensions in preterm and control full-term born individuals. DATA COLLECTION AND ANALYSIS: Following study retrieval and selection, relevant data were extracted, and the Newcastle-Ottawa scale was used to assess the selection, comparability, and outcome domains. Exploratory synthesis and meta-regression were carried out using the random effects model. RESULTS: Three studies were located from the initially retrieved records and the assessments with the Newcastle-Ottawa scale identified issues regarding the selection and comparability domains. Overall, the mesiodistal and the buccolingual dimensions of the permanent teeth in both dental arches tended to be smaller in children born prematurely than full term children. Subgroup analyses showed statistically significant differences for the extremely preterm to control group comparisons for the incisors and the first molars. Meta-regression showed a modificatory effect of gestational age and racial background but not of birth weight and gender on tooth size. The quality of available evidence was rated at best as moderate. CONCLUSIONS: Premature birth could potentially be associated with reduced tooth-crown dimensions in some permanent teeth especially in children born extremely preterm. Although the results from these observational studies should be approached with caution until more information becomes available, the possible clinical implications in terms of diagnosis and treatment planning should be considered. REGISTRATION: PROSPERO (CRD42020182243).
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.013 | 0.003 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".