Lung Recruitment Using High-Frequency Oscillation Volume Guarantee in Preterm Infants with Evolving Bronchopulmonary Dysplasia
Bibliographic record
Abstract
<b><i>Background:</i></b> Stepwise lung recruitment maneuvers (LRMs) may be used in ventilated preterm infants. However, its use in high-frequency oscillation with volume guarantee (HFO-VG) is not well studied. <b><i>Methods:</i></b> Preterm infants treated with HFO-VG who had LRMs were identified. Patient and respiratory parameters were recorded. <b><i>Results:</i></b> Ten infants, median GA 25<sup>+6</sup> (IQR 24<sup>+2</sup>–27<sup>+0</sup>) weeks, and 21 LRMs were identified. LRMs were performed at a median age of 26 days, with a starting MAP of 16 (14–17) cm H<sub>2</sub>O and the highest MAP of 23.5 (22.0–24.8) cm H<sub>2</sub>O. Most (76%) resulted in immediate improved SpO<sub>2</sub>/FiO<sub>2.</sub> There were no sustained differences in median oxygen saturation index (8.4 vs. 9, <i>p</i> = 0.09), SpO<sub>2</sub>/FiO<sub>2</sub> (1.8 vs. 1.8, <i>p</i> = 0.8), ∆P (21 vs. 23, <i>p</i> = 0.64), or transcutaneous CO<sub>2</sub> (58 vs. 60, <i>p</i> = 0.84) in 24 h before and after LRMs. <b><i>Conclusions:</i></b> In preterm infants with evolving bronchopulmonary dysplasia, LRMs on HFO-VG did not result in sustained improvement to oxygenation or ventilation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".