Bibliographic record
Abstract
<p>Akne vulgaris adalah penyakit kulit paling umum dan dikaitkan dengan kecemasan, penurunan harga diri, stigma, dan skar pada wajah yang dapat menjadi beban penyakit yang signifikan bagi pasien. Pada kasus akne nodulokistik dan papulopustular yang berat, isotretinoin oral sering diresepkan sebagai terapi lini pertama yang berpotensi menyembuhkan penyakit. Pedoman praktik klinis Kanada, Amerika, dan Eropa merekomendasikan isotretinoin untuk penatalaksanaan akne derajat sedang hingga berat. Meskipun penggunaan klinis isotretinoin telah berlangsung bertahun-tahun, tinjauan komprehensif terapi isotretinoin pada pasien akne masih kurang. Artikel ini akan memaparkan penggunaan isotretinoin oral pada tatalaksana akne vulgaris.</p><p>Acne vulgaris is the most common skin disease and the associated anxiety, reduced self-esteem, stigma, and facial scarring can impose a significant burden on the patient. In cases of severe nodulocystic and papulopustular acne, oral isotretinoin is often prescribed as a first-line treatment, potentially cure of disease. Canadian, American, and European clinical practice guidelines have suggested that isotretinoin should be used for management of moderate to severe acne. Despite many years of clinical use of isotretinoin, a comprehensive review of evidence for isotretinoin therapy for acne is lacking. This article describes the use of oral isotretinoin in the treatment of acne vulgaris.</p>
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.009 | 0.003 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".