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Abstract 13657: Malignant Multivessel Coronary Spasm

2021· article· en· W3214694886 on OpenAlexaff
Ana Inashvili, Ruifang Yang, Benjamin Kilpatrick, David Goldgrab, Héctor López-de la Garza, Devansh Patel, Tehreen Khan, Robert Dewhurst, Stephen Mester, William J. Bugni

Bibliographic record

VenueCirculation · 2021
Typearticle
Languageen
FieldMedicine
TopicCardiac Imaging and Diagnostics
Canadian institutionsBrandon Regional Health Authority
Fundersnot available
KeywordsMedicineCardiologyInternal medicine

Abstract

fetched live from OpenAlex

Objective: Management of multivessel coronary spasm is challenging. Case: A 59-year-old female with a medical history of CAD status post coronary stents presented with atypical chest pain.The following morning the patient suffered a PEA arrest, from which she was resuscitated. Retrospective review of telemetry revealed frequent episodes of transient ST segment elevations in inferior leads, lasting minutes, eventually followed by sinus bradycardia and episodes of high-degree AV block with pauses up to 20 seconds.Two weeks earlier the patient presented at another institution with similar complaints. Inferior STEMI was diagnosed, she received 2 DES, in proximal OM1 and Mid LAD. She represented 6 days later with continued symptoms and repeat catheterization revealed patent stents. She was reassured and discharged on Isosorbide Mononitrate in addition to Carvedilol. Management and Decision Making: Coronary angiography at our facility demonstrated 90% stenosis of proximal LCX and 60-70% of proximal LAD. These stenosis resolved with intracoronary nitroglycerin. The stents were patent. Therefore, she was diagnosed with coronary spasm. During her hospital stay, the patient did have four more episodes of ST elevations associated with complete heart block. Since she developed high degree AV block after a coronary spasm, a temporary pacemaker was placed. Norvasc as well as nitroglycerin drip were used to treat her coronary vasospasm. Pure B-blocker medications were avoided to prevent unbalanced alpha effect.The patient was extubated 4 days later and fully recovered neurologically. A permanent pacemaker was placed and discharged home. Conclusion: High suspicion is important for diagnosis of coronary vasospasm. Treatment with coronary vasodilators is cornerstone of management. We also avoided pure alpha agonists during resuscitation measures, as well as pure B-blocker medications after recovery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.033

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0100.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.283
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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