Circumcision in patients with bleeding disorders: Can it be done safely?
Bibliographic record
Abstract
Purpose: The purpose of our study was to review outcome of circumcision among children with bleeding disorders at our institution and also to determine the impact of optimization leading to safe circumcision. Methods: Data representing boys (age 0-16 years) who underwent routine circumcision at the Aga Khan University Hospital (AKUH) between1988-2014 was retrospectively reviewed. Children with bleeding disorder were identified using International Classification of Diseases (ICD) Code 64.0. Data was retrieved and confidentially was maintained. SPSS version 19 was used for statistical analysis. Results: During 26 years 13,200 circumcisions were performed at AKUH. Amongst these 8,463 (64.11%) were done by using Plastibell, while 4,737 (35.88%) by open slit method. Only 23 (0.17%) children were identified with bleeding disorder. Two groups were made, Group-A (n:15) children with known bleeding disorders having circumcision and GroupB, (n:8) those in whom bleeding disorder was diagnosed after circumcision. Median age of children in Group-A was 9 years. All children in Group-A underwent open circumcision. 10 patients had Factor VIII deficiency, 2 had Glanzmann’s thrombasthenia, 1 had Factor IX deficiency, 1 had Quebec platelet disorder, and 1 had Von Willebrand disorder. Median age of children in Group-B was 3 months. 7 out of 8 underwent plastibell while one had circumcision by open technique. 7 were diagnosed as Factor VIII deficiency and 1 diagnosed later to have Glanzmann's thrombasthenia. Statistical analysis showed significant difference among these two groups’ p-value with respect to age (p-value 0.00) and family history (p-value 0.04- Fisher’s exact test). Both groups had similar postoperative length of stay. Overall bleeding complication rate after optimization was 13.33%. Conclusion: With the help of hematologist and adequate Factor replacement, these children can be managed as daycare. We suggest risks and benefit should be discussed with parents before procedure
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".