Sex Differences in the Anatomical Distribution of Melanocytic Nevi in Canadian Hutterite Children
Bibliographic record
Abstract
BACKGROUND: Studies of the distribution of melanocytic nevi (MN) and/or cutaneous malignant melanoma (CMM) in white populations have commonly observed greater numbers of MN and CMM on the torsos of males and on the limbs of females. The most commonly cited explanation for this sex difference is differential sunlight exposure of body subsites due to gender differences in clothing styles and recreational activities. Less common, but more speculative, explanations suggest hormonal differences or regional differences in melanocytes across body subsites. OBJECTIVE: The purpose of the present study was to evaluate these explanations in light of sex differences in the anatomical distribution of nevi in Canadian Hutterite children whose traditional religious costume protects them from sun exposure. METHODS: Nevi counts from 178 male and 154 female children, aged 5 to 15 years, from 23 Central Alberta Hutterite colonies were broken down by age and body subsite. RESULTS: At age levels from 6 to 15 years, males had greater nevus counts on the torso, whereas females had greater counts on the upper and lower limbs. CONCLUSION: The appearance of this distribution of nevi in sun-protected children as early as age 6 is problematic for explanations based on differential sunlight exposure and hormonal changes at puberty.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".