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Record W4200293789 · doi:10.1002/pds.5404

Data sources for drug utilization research in Latin American countries—A cross‐national study: <scp>DASDUR‐LATAM</scp> study

2021· article· en· W4200293789 on OpenAlexaff
Luciane Cruz Lopes, Maribel Salas, Cláudia Garcia Serpa Osorio-de-Castro, Lisiane Freitas Leal, Svetlana V. Doubova, Martín Cañás, Anahí Dreser, Ángela Acosta, André Oliveira Baldoni, Cristiane de Cássia Bergamaschi, Daniel Marques Mota, Diana Lizbeth Gómez-Galicia, Dino Sepúlveda, Edgard Narvaez Delgado, Elisângela da Costa Lima, Felipe Vera, Felipe Ferré, Gustavo H. Marín, I. Cánovas Olmos, Ivan Ricardo Zimmermann, Izabela Fulone, Juan Roldán‐Saelzer, Juan Carlos Sánchez‐Salgado, Lucila I. Castro‐Pastrana, Luiz Júpiter Carneiro de Souza, Manuel Machado Beltrán, Marcus Tolentino Silva, María Belén Mena, Marta Maria de França Fonteles, Martín Urtasun, Mónica Tarapués, Patricia Granja, Natalia Medero, Raquel Herrera Comoglio, Sílvio Barberato-Filho, Taís Freire Galvão, Vera Lúcia Luiza, Yared Santa‐Ana‐Téllez, L. Yesenia Rodríguez‐Tanta, Monique Elseviers

Bibliographic record

VenuePharmacoepidemiology and Drug Safety · 2021
Typearticle
Languageen
FieldMedicine
TopicPharmaceutical Practices and Patient Outcomes
Canadian institutionsMcGill University Health Centre
FundersEidgenössisches NuklearsicherheitsinspektoratCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
KeywordsMedicinePharmacyLatin AmericansPublic healthPharmacoepidemiologyGovernment (linguistics)Family medicinePolitical sciencePharmacologyNursing

Abstract

fetched live from OpenAlex

PURPOSE: Drug utilization research (DUR) contributes to inform policymaking and to strengthen health systems. The availability of data sources is the first step for conducting DUR. However, documents that systematize these data sources in Latin American (LatAm) countries are not known. We compiled the potential data sources for DUR in the LatAm region. METHODS: A network of DUR experts from nine LatAm countries was assembled and experts conducted: (i) a website search of the government, academic, and private health institutions; (ii) screening of eligible data sources, and (iii) liaising with national experts in pharmacoepidemiology (via an online survey). The data sources were characterized by accessibility, geographic granularity, setting, sector of the data, sources and type of the data. Descriptive analyses were performed. RESULTS: We identified 125 data sources for DUR in nine LatAm countries. Thirty-eight (30%) of them were publicly and conveniently available; 89 (71%) were accessible with limitations, and 18 (14%) were not accessible or lacked clear rules for data access. From the 125 data sources, 76 (61%) were from the public sector only; 46 (37%) were from pharmacy records; 43 (34%) came from ambulatory settings and; 85 (68%) gave access to individual patient-level data. CONCLUSIONS: Although multiple sources for DUR are available in LatAm countries, the accessibility is a major challenge. The procedures for accessing DUR data should be transparent, feasible, affordable, and protocol-driven. This inventory could permit a comparison of drug utilization between countries identifying potential medication-related problems that need further exploration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.012
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.273
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0160.012
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.500
GPT teacher head0.582
Teacher spread0.082 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2021
Admission routes1
Has abstractyes

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