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Record W4200299955 · doi:10.1002/acm2.13494

Deep‐learning‐assisted algorithm for catheter reconstruction during MR‐only gynecological interstitial brachytherapy

2021· article· en· W4200299955 on OpenAlexaff
Amani Shaaer, Moti Paudel, Mackenzie Smith, Frances Tonolete, Ananth Ravi

Bibliographic record

VenueJournal of Applied Clinical Medical Physics · 2021
Typearticle
Languageen
FieldMedicine
TopicEndometrial and Cervical Cancer Treatments
Canadian institutionsUniversity of TorontoSunnybrook Health Science CentreHealth Sciences CentreToronto Metropolitan University
Fundersnot available
KeywordsBrachytherapyContouringAlgorithmComputer scienceMagnetic resonance imagingWorkflowCatheterDeep learningNuclear medicineThresholdingArtificial intelligenceMedicineRadiologyRadiation therapyImage (mathematics)

Abstract

fetched live from OpenAlex

Magnetic resonance imaging (MRI) offers excellent soft-tissue contrast enabling the contouring of targets and organs at risk during gynecological interstitial brachytherapy procedure. Despite its advantage, one of the main obstacles preventing a transition to an MRI-only workflow is that implanted plastic catheters are not reliably visualized on MR images. This study aims to evaluate the feasibility of a deep-learning-based algorithm for semiautomatic reconstruction of interstitial catheters during an MR-only workflow. MR images of 20 gynecological patients were used in this study. Note that 360 catheters were reconstructed using T1- and T2-weighted images by five experienced brachytherapy planners. The mean of the five reconstructed paths were used for training (257 catheters), validation (15 catheters), and testing/evaluation (88 catheters). To automatically identify and localize the catheters, a two-dimensional (2D) U-net algorithm was used to find their approximate location in each image slice. Once localized, thresholding was applied to those regions to find the extrema, as catheters appear as bright and dark regions in T1- and T2-weighted images, respectively. The localized dwell positions of the proposed algorithm were compared to the ground truth reconstruction. Reconstruction time was also evaluated. A total of 34 009 catheter dwell positions were evaluated between the algorithm and all planners to estimate the reconstruction variability. The average variation was 0.97 ± 0.66 mm. The average reconstruction time for this approach was 11 ± 1 min, compared with 46 ± 10 min for the expert planners. This study suggests that the proposed deep learning, MR-based framework has potential to replace the conventional manual catheter reconstruction. The adoption of this approach in the brachytherapy workflow is expected to improve treatment efficiency while reducing planning time, resources, and human errors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.987
Threshold uncertainty score0.896

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.040
GPT teacher head0.358
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2021
Admission routes1
Has abstractyes

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