MétaCan
Menu
Back to cohort
Record W4205387540 · doi:10.1002/jbm4.10414

Erratum for Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the <scp>ACTIVE</scp> Study

2020· erratum· en· W4205387540 on OpenAlexaff
Ruban Dhaliwal, Didier Hans, Gary Hattersley, Bruce Mitlak, Lorraine A. Fitzpatrick, Yamei Wang, Ann V. Schwartz, Paul D. Miller, Robert G. Josse

Bibliographic record

VenueJBMR Plus · 2020
Typeerratum
Languageen
FieldMedicine
TopicBone health and osteoporosis research
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsTeriparatidePlaceboMedicinePost-hoc analysisOsteoporosisAdverse effectInternal medicineClinical endpointType 2 diabetesType 2 Diabetes MellitusDiabetes mellitusClinical trialEndocrinologyBone mineralPathologyAlternative medicine

Abstract

fetched live from OpenAlex

This article corrects the following: Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study Ruban Dhaliwal, Didier Hans, Gary Hattersley, Bruce Mitlak, Lorraine A Fitzpatrick, Yamei Wang, Ann V Schwartz, Paul D Miller, Robert G Josse Volume 4, Number 4, Journal of Bone and Research Plus page e10346 JBMR Plus. 2020 Feb 27;4(4):e10346. doi: 10.1002/jbm4.10346. eCollection 2020 Apr. First published online: https://doi.org/10.1002/jbm4.10346 “At 6 months, mean percent change from baseline in lumbar spine TBS was 2.63% (95% CI, 1.54% to 3.72%) in the abaloparatide group, 1.32% (95% CI, 0.38% to 2.26%) in the teriparatide group, and −0.10% (95% CI, −1.14% to 0.94%) in the placebo group (P < 0.01 for abaloparatide versus placebo and P < 0.05 for teriparatide versus placebo; difference between abaloparatide and teriparatide was not significant).”(1) ACTIVE = Abaloparatide Comparator Trial In Vertebral Endpoints; T2DM = type 2 diabetes mellitus. aIndicates adverse events that occurred in at least 5% of patients (in any arm) with T2DM in ACTIVE. bFour patients with a reported adverse event of T2DM were marked “condition aggravated.” cHypercalcemia was defined as albumin-corrected serum calcium value ≥10.7 mg/dL (≥2.67 mmol/L) at any time point, which was a prespecified secondary endpoint. In Fig. 1, the “Ns” were reported incorrectly for the teriparatide (TPTD) and placebo (PBO) treatment groups. This error has now been corrected in the revised Fig. 1 shown here. The authors regret any confusion and inconvenience this may have caused the readers of JBMR Plus. The main conclusion of the study, that abaloparatide treatment resulted in significant improvements in BMD and lumbar spine TBS compared with placebo in the T2DM population, was not affected by the errors. The peer review history for this article is available at https://publons.com/publon/10.1002/jbm4.10414. The peer review history for this article is available at https://publons.com/publon/10.1002/jbm4.10414.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.649
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.303
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueJBMR PlusSame topicBone health and osteoporosis researchFrench-language works237,207