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A Graph Attention Neural Network for Diagnosing ASD with fMRI Data

2021· article· en· W4206187231 on OpenAlexaff
Wutao Yin, Longhai Li, Fang‐Xiang Wu

Bibliographic record

Venue2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · 2021
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsUniversity of Saskatchewan
FundersScience and Engineering Research Council
KeywordsFunctional magnetic resonance imagingComputer scienceAutism spectrum disorderNeuroimagingGraphArtificial intelligenceGraph theoryResting state fMRIMachine learningPower graph analysisArtificial neural networkPattern recognition (psychology)AutismNeurosciencePsychologyTheoretical computer sciencePsychiatry

Abstract

fetched live from OpenAlex

Autism Spectrum Disorder (ASD) is a common psychiatric disorder disease that typically causes impaired communication and compromised social interactions. Functional magnetic resonance imaging (fMRI) data is one of the common neuroimaging modalities for understanding human brain functionalities as well as the diagnosis and treatment of brain disorders. There are many successful applications of deep learning to fMRI analytics where fMRI data is mostly considered structured Euclidean grids or time series, and features were usually extracted from the computer vision or time series perspective. Graph neural networks (GNNs) are neural networks that learn the interactions of graphs via message passing between the nodes of graphs. Recently variants of GNNs such as graph attention network (GAT) have demonstrated outstanding performances on many machine learning tasks. In this paper, we proposed a connectivity based graph attention network for autism diagnosis using functional connectivity (FC) patterns obtained from resting-state fMRI (rs-fMRI). We define graphs based on F Cs and statistics of fMRI time series and present a connectivity-based GATs model for fMRI data analysis. The graph-theoretic based approach enables us to pass messages among connectomic (Non-Euclidean) neighborhoods, which is consistent with the brain functional networks. To evaluate the performance of our proposed GAT, we apply the GAT model to the classification of A SD patients from normal controls. Our results show that GAT can effectively capture salient features for ASD classifications in fMRI analysis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.014
Threshold uncertainty score0.028

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.329
Teacher spread0.194 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2021
Admission routes1
Has abstractyes

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