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Record W4206473000 · doi:10.21203/rs.3.rs-1212185/v1

The Cognitive Impairment At Acute Stage After Intracerebral Hemorrhage

2022· preprint· en· W4206473000 on OpenAlexaboutno aff
Shoujiang You, Cong Gu, Wei Zhang, Jiayun Wang, Jiaping Xu, Jing Liu, Hua Hu, Yongjun Cao

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicIntracerebral and Subarachnoid Hemorrhage Research
Canadian institutionsnot available
FundersSoochow UniversityGovernment of Jiangsu ProvinceNational Natural Science Foundation of China
KeywordsMontreal Cognitive AssessmentMedicineOdds ratioCognitionConfidence intervalInternal medicineLogistic regressionIntracerebral hemorrhageStage (stratigraphy)Cognitive impairmentHematomaAnesthesiaSurgeryDiseasePsychiatry

Abstract

fetched live from OpenAlex

Abstract Background: We determined the frequency and factors of cognitive impairment at acute stage and investigate the prognostic effect of the cognitive function at acute stage on the delayed cognitive impairment after acute intracerebral hemorrhage (ICH). Methods: A total of 208 patients with acute ICH were enrolled from January 2017 to February 2019. Cognitive function was assessed during the acute stage and follow-up after ICH using Montreal Cognitive Assessment (MoCA) score. The significant acute stage and delayed cognitive impairment was defined as a MoCA score <20 within 1 week after hospital admission and during follow-up respectively. Results: During a mean 20 (IQC 17-23) months follow-up, 185 patients with follow-up cognitive function data. There are 89 (42.8%) and 86 (46.5%) patients had acute stage and delayed significant cognitive impairment respectively. The older age, large baseline hematoma volume, more severe ICH, and low level of education were significant associated with significant cognitive impairment at acute stage (all P<0.009). In the multivariable logistic regression model, the low acute phase MoCA score (odds ratio [OR] 0.59; 95% confidence interval [CI] 0.48-0.71; P<0.001) was the only one independent factor associated with delayed significant cognitive impairment after ICH. Conclusions: Near half of patients have significant cognitive impairment at acute stage after ICH, which is more frequent in the elderly, those with large baseline hematoma volume, and more severe initial neurological deficit. The acute phase MoCA score was independent increased the risk of delayed cognitive impairment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.392
Teacher spread0.354 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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