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Record W4206658646 · doi:10.21203/rs.3.rs-744878/v1

ITS-2 rDNA Nemabiome Metabarcoding in two Isolated Populations of Wild Roe Deer (Capreolus Capreolus) Reveals Variation in Gastrointestinal Nematode Community Composition Between Regions and Among Age Classes

2021· preprint· en· W4206658646 on OpenAlexafffund
Camille Beaumelle, Libby Redman, Jill de Rijke, Janneke Wit, Slimania Benabed, François Débias, Jeanne Duhayer, Sylvia Pardonnet, Marie‐Thérèse Poirel, Gilles Capron, Stéphane Chabot, Benjamin Rey, Glenn Yannic, John S. Gilleard, Gilles Bourgoin

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldVeterinary
TopicHelminth infection and control
Canadian institutionsUniversity of Calgary
FundersNatural Sciences and Engineering Research Council of CanadaVetAgro Sup
KeywordsBiologyCapreolusRoe deerOstertagiaZoologyUngulateNematodeTeladorsagia circumcinctaEcologyTrichostrongylusHaemonchus contortusHabitat

Abstract

fetched live from OpenAlex

Abstract Background Gastrointestinal nematodes are ubiquitous for both domestic and wild ungulates which have varying consequences to health and fitness. They exist as complex communities of multiple co-infecting species and we have a very limited understanding of how these communities vary in different hosts, regions and circumstances or on how this affects their impacts. Methods We have undertaken ITS-2 rDNA nemabiome metabarcoding on populations of nematode larvae isolated from fecal samples of roe deer of different sex and age classes in the two isolated populations of Chizé and Trois Fontaines in France not co-grazing with any domestic ungulate species. Results We identified 100 Amplified Sequence Variants (ASVs) that assigned to 14 gastrointestinal nematode taxa overall either at genus (38%), or species (62%) level. These taxa were dominated by parasites classically found in cervids - e.g., Ostertagia leptospicularis , Spiculopteragia spp. Higher parasite species diversity was present in the Trois Fontaine than in the Chize populations including the presence of some species more typically seen in domestic livestock, ( Haemonchus contortus , Bunostomum trigonocephalum , Cooperia punctata , Teladorsagia circumcincta ). No differences in parasite species diversity or community composition was seen in the samples collected from three zones of differing habitat quality within the Chize region. Young roe deer hosted the highest diversity of gastrointestinal nematodes, with more pronounced effects of age apparent in Trois Fontaines. The effect of host age differed between gastrointestinal nematode species, e.g. there was little effect on Ostertagia leptospicularis but a high effect on Trichostrongylus spp. No effect of host sex was detected in either site. Conclusions The presence of some livestock parasite species in the Trois Fontaine roe deer popualtions was surprising given the isolation of this population away from grazing domestic livestock. However, it should be noted that a small group of sheep were resident in the region, albeit separately fenced, which raises some interesting questions regarding the introduction of non-native parasite species into wildlife populations. Overall, our results suggest complex interactions between hosts, environments and parasites and illustrate the power of the nemabiome metabarcoding approach to elucidate the composition of gastrointestinal nematode communities in wildlife.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.065
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.004
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.216
GPT teacher head0.451
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes2
Has abstractyes

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