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Record W4210400893 · doi:10.1183/23120541.00643-2021

ERS International Congress 2021: highlights from the Paediatric Assembly

2022· review· en· W4210400893 on OpenAlexaff
Cristina Ardura‐Garcia, Alicia Abellan, Sara Cuevas Ocaña, Nadine Freitag, Yin Ting Lam, Heidi Makrinioti, Monique Slaats, Matteo Storti, Emma Williams, Theodore Dassios, Liesbeth Duijts, Refika Ersu, Stojka Fustik, Rory E. Morty, Marijke Proesmans, Dirk Schramm, Sejal Saglani, Alexander Mœller, Marielle W. Pijnenburg

Bibliographic record

VenueERJ Open Research · 2022
Typereview
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsChildren's Hospital of Eastern OntarioUniversity of Ottawa
FundersDeutsches Zentrum für LungenforschungBundesministerium für Bildung und ForschungZonMwMax-Planck-GesellschaftDeutsche ForschungsgemeinschaftEuropean Respiratory SocietySanofiSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungUniversitätsklinikum HeidelbergNational Science Foundation
KeywordsMedicineBronchopulmonary dysplasiaBronchiectasisAsthmaIntensive care medicineAllergic bronchopulmonary aspergillosisEpidemiologyPediatricsPrimary ciliary dyskinesiaCystic fibrosisBronchiolitisRespiratory systemLungPathologyImmunologyInternal medicinePregnancyGestational age

Abstract

fetched live from OpenAlex

In this review, Early Career Members of the European Respiratory Society (ERS) and the Chairs of the ERS Assembly 7: Paediatrics present the highlights in paediatric respiratory medicine from the ERS International Congress 2021. The eight scientific Groups of this Assembly cover respiratory physiology and sleep, asthma and allergy, cystic fibrosis (CF), respiratory infection and immunology, neonatology and intensive care, respiratory epidemiology, bronchology, and lung and airway development. We here describe new developments in lung function testing and sleep-disordered breathing diagnosis, early life exposures affecting pulmonary function in children and effect of COVID-19 on sleep and lung function. In paediatric asthma, we present the important role of the exposome in asthma development, and how biologics can provide better outcomes. We discuss new methods to assess distal airways in children with CF, as some details remain blind when using the lung clearance index. Moreover, we summarise the new ERS guidelines for bronchiectasis management in children and adolescents. We present interventions to reduce morbidity and monitor pulmonary function in newborns at risk of bronchopulmonary dysplasia and long-term chronic respiratory morbidity of this disease. In respiratory epidemiology, we characterise primary ciliary dyskinesia, identify early life determinants of respiratory health and describe the effect of COVID-19 preventive measures on respiratory symptoms. Also, we describe the epidemiology of interstitial lung diseases, possible consequences of tracheomalacia and a classification of diffuse alveolar haemorrhage in children. Finally, we highlight that the characterisation of genes and pathways involved in the development of a disease is essential to identify new biomarkers and therapeutic targets.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Open science, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.836
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0110.005
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.003
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0070.008
Research integrity0.0000.006
Insufficient payload (model declined to judge)0.0380.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.408
GPT teacher head0.561
Teacher spread0.153 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes1
Has abstractyes

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