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Effect of barley protein supplementation on coronary heart disease risk reduction

2008· article· en· W4210648790 on OpenAlexaboutno aff

Bibliographic record

VenueThe FASEB Journal · 2008
Typearticle
Languageen
FieldNursing
TopicFood composition and properties
Canadian institutionsnot available
Fundersnot available
KeywordsCrossover studyPlaceboCoronary heart diseaseInternal medicineBlood lipidsMedicineWeight lossAnimal scienceEndocrinologyFood scienceCholesterolChemistryBiologyObesity

Abstract

fetched live from OpenAlex

Objective: High animal protein weight loss diets have been associated with rises in LDL‐C. We wished to determine the effect of high barley protein intake on LDL‐C. Method: 23 hypercholesterolemic individuals (16F, 7M; 57±7y; LDL‐C, 3.90±0.21mmol/L) completed two 4‐week treatments of bread supplementation containing either 30g/d (based on a 2000 kcal diet) of barley protein (treatment group) or dairy protein (calcium caseinate placebo), in a randomized controlled crossover design. Serum lipids, body weight and blood pressure were measured biweekly on each treatment. Results: At week 4, changes expressed as the difference between baseline demonstrated no evidence that barley protein supplementation altered LDL‐C and TChol:HDL‐C (−0.09±0.11mmol/L, P=0.454 and 0.13±0.14mmol/L, P=0.364, respectively). Corresponding data for the dairy protein supplementation also showed no overall improvement (LDL‐C, 0.00±0.11mmol/L, P=0.989 and TChol:HDL‐C, 0.19±0.11mmol/L, P=0.088). Furthermore, the effect of barley protein on blood lipids was not significantly different from dairy protein (LDL‐C, P=0.836; TChol:HDL‐C, P=0.964). Conclusion: This study demonstrates that neither barley nor dairy protein appear to alter blood lipids and may be equally suitable for weight reduction diets. Funding: Natural Sciences and Engineering Research Council of Canada, Loblaws Ltd.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.264
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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