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Record W4212793211 · doi:10.2337/cd21-0044

Could Overt Diabetes Be Triggered by Abuse of Selective Androgen Receptor Modulators and Growth Hormone Secretagogues? A Case Report and Review of the Literature

2022· article· en· W4212793211 on OpenAlexaffabout
Richard Sotorník, Roguel Suissa, Jean-Luc Ardilouze

Bibliographic record

VenueClinical Diabetes · 2022
Typearticle
Languageen
FieldMedicine
TopicPharmacology and Obesity Treatment
Canadian institutionsCentre Hospitalier Universitaire de Sherbrooke
Funderslékařská fakulta Univerzity KarlovyUniverzita Karlova v Praze
KeywordsCitationIconMedicineDownloadInternal medicineLibrary scienceWorld Wide WebComputer science

Abstract

fetched live from OpenAlex

Case Studies| July 01 2022 Could Overt Diabetes Be Triggered by Abuse of Selective Androgen Receptor Modulators and Growth Hormone Secretagogues? A Case Report and Review of the Literature Richard Sotorník 0000-0003-0813-3951 ; Richard Sotorník 1Canadian Medical, Prague, Czech Republic2Third Faculty of Medicine, Charles University, Prague, Czech Republic Search for other works by this author on: This Site PubMed Google Scholar Roguel Suissa; Roguel Suissa 1Canadian Medical, Prague, Czech Republic Search for other works by this author on: This Site PubMed Google Scholar Jean-Luc Ardilouze 0000-0001-8160-0320 Jean-Luc Ardilouze 3Division of Endocrinology, University Hospital Center, Sherbrooke, Canada Search for other works by this author on: This Site PubMed Google Scholar Corresponding author: Richard Sotorník, richard.sotornik@lf3.cuni.cz Clin Diabetes 2022;40(3):373–379 https://doi.org/10.2337/cd21-0044 PubMed: 35983415 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation Richard Sotorník, Roguel Suissa, Jean-Luc Ardilouze; Could Overt Diabetes Be Triggered by Abuse of Selective Androgen Receptor Modulators and Growth Hormone Secretagogues? A Case Report and Review of the Literature. Clin Diabetes 1 July 2022; 40 (3): 373–379. https://doi.org/10.2337/cd21-0044 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Diabetes Search Advanced Search In October 2018, a 47-year-old male recreational bodybuilder presented to his general practitioner in Prague, Czech Republic, with polydipsia (daily fluid intake 5–6 L), polyuria, blurred vision, malaise, and weight loss of 10 kg in the past month. He did not complain of any pain or fever and was taking no regular medication except recent (3 months) use of performance-enhancing drugs (PEDs) purchased from a fitness center, including two selective androgen receptor modulators (SARMs)—RAD140 5 mg twice daily and andarine 25 mg twice daily, 5 days per week—as well as the growth hormone (GH) secretagogue (GHS)/ghrelin analog ibutamoren 25 mg daily, 5 days per week. He had no previous use of hormonal supplements. The patient reported no serious disease apart from borreliosis in 2012, seasonal pollinosis, and minor injuries related to physical activities. Three years before this visit, he underwent a routine general check-up. At that time, his weight was... You do not currently have access to this content.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.221
Threshold uncertainty score0.498

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.321
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2022
Admission routes2
Has abstractyes

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