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Analysis of SARS-CoV-2 and factors predicting next spillover of its more contagious variant.

2021· article· en· W4213014858 on OpenAlexaff
Syed A. Aziz, Kaneez Fatima Shad

Bibliographic record

VenueINTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE RESEARCH (IJEHSR) · 2021
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicCOVID-19 Pandemic Impacts
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Sars virusSpillover effect2019-20 coronavirus outbreakVirologyComputational biologyBiologyMedicineEconomicsOutbreakInfectious disease (medical specialty)Internal medicine

Abstract

fetched live from OpenAlex

Background: At the beginning of 2020, the world has started experiencing the epidemic of a novel coronavirus; by the mid of March 2020, it has been declared a pandemic. The disease has been named COVID-19, and the virus is labelled as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on the type of infection it is causing. Coronaviruses are not new to us, and there are 15 different coronaviruses known to us. In the last 20 years, this is the fourth coronavirus pandemic, and SARS-CoV-2 seems to be the deadliest among all, with the ability to continue producing more contagious variants.
 Methodology: In this review, we used EMBASE, MEDLINE and PubMed database search engines (retrieval systems) for the words SARS-CoV-2, its origin, transmission, tropism, zoonotic, vaccines, and the factors that contribute to its contagious and virulent nature.
 Results: Accumulating evidence indicated that the pandemic might have a massive impact on both physical and mental health, particularly on those predisposed to COVID-19. Approved vaccines are in use around the globe, they may show different effects in future. We observe signs of constant mutation of SARS-CoV-2, recently SARS-CoV-2 variants such as delta and C.1.2.
 Conclusion: In this review, we endeavour to reveal the factors which can impede the ability of this highly lethal virus to reproduce into more contagious variants.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.066
Threshold uncertainty score0.839

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0030.002
Science and technology studies0.0000.001
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.261
GPT teacher head0.467
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2021
Admission routes1
Has abstractyes

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