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Stage I testicular cancer: Five-year follow-up rates and reasons for non-adherence.

2022· article· en· W4213047087 on OpenAlexaff
Tim Karmas, Patrick Holland, Kara Matheson, Lori Wood

Bibliographic record

VenueJournal of Clinical Oncology · 2022
Typearticle
Languageen
FieldMedicine
TopicTesticular diseases and treatments
Canadian institutionsQueen Elizabeth II Health Sciences CentreNova Scotia Health AuthorityDalhousie University
Fundersnot available
KeywordsMedicineCancerStage (stratigraphy)SeminomaTesticular cancerMilestoneCohortInternal medicinePediatricsGynecologySurgeryChemotherapy

Abstract

fetched live from OpenAlex

412 Background: For stage I testicular cancer patients, active surveillance or follow up (f/u) post treatment is an integral part of quality care. Most guidelines recommend a minimum of 5 years of f/u however, it is known that a significant proportion of patients do not meet this milestone. The goal of this project was to determine what proportion of patients did not undergo ≥ 5 years of f/u in Nova Scotia (NS) and to document the reasons why. This would allow one to develop strategies to improve compliance and quality care. Methods: A review of all patients from NS diagnosed with testicular cancer between 2006-2015 was conducted. REB approval was obtained. Data from the provincial registry and electronic medical records was used to determine date of diagnosis, relapse/death, and f/u dates. Complete f/u was defined as: a patient having tumor markers, imaging studies, and/or clinical documentation ≥ 5 after initial diagnosis or relapse. The adequacy of f/u investigations was not recorded. If follow up was < 5 years, the reason for this was recorded. Results: In this cohort, 151 patients had stage I testicular cancer; 108 with seminoma (75% on surveillance) and 43 with nonseminoma (93% on surveillance). The median age was: 35.8 years. 48 pts (31.8%) were not seen at a cancer center (until relapse in 5 pts). Excluding 2 pts who died of unrelated causes, 44 patients (29.5%) had < 5 years f/u in NS. The most common reasons were: moved or probably moved in 17 (38.6%) and patient compliance/missing ≥2 appointments in 10 (22.7%). Modifiable reasons for incomplete f/u include: discharged too early from the cancer center in 3 patients, f/u never arranged post orchiectomy in 2 patients, and care transferred to primary care which did not occur in 1 patient. 22 patients relapsed: 3 in patients with lack of ≥ 5 years of f/u causing excess morbidity in 1 case. No patients died of testicular cancer. Conclusions: The majority of men with stage I testicular cancer had ≥ 5 years of f/u in NS as recommended by guidelines. However, 30% did not, with the most common reason being that the patient moved in 39% (where they may or may not have had f/u) and noncompliance in 23%. This study reinforces the need to have a seamless transition of care for this young, mobile patient population and easy, automated, regular appointment reminders. These results have led us to explore the creation of a phone-based app to improve follow up care and transition of care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.066
Threshold uncertainty score0.132

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.474
Teacher spread0.370 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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