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Record W4213279521 · doi:10.1016/j.xjon.2022.02.013

New or enlarging hiatal hernias after thoracic surgery for early lung cancer

2022· article· en· W4213279521 on OpenAlexfundno aff
Kimberly J. Song, Rowena Yip, Michael Chung, Qiang Cai, Yeqing Zhu, Ayushi Singh, Erik E. Lewis, David F. Yankelevitz, Emanuela Taioli, Claudia I. Henschke, Raja M. Flores, Andrew Kaufman, Dong‐Seok Lee, Daniel Nicastri, Andrea Wolf, Kenneth E. Rosenzweig, Jorge Gómez, Mary Beth Beasley, Maureen F. Zakowski, Rebecca M. Schwartz, Huiwen Chan, Jeffrey Zhu, Sydney Kantor, Shana Adler, Wissam Raad, Zrzu Buyuk, Adie Friedman, Ronald Dreifuss, Stacey Verzosa, Mariya Yakubox, Karina Aloferdova, Patricia Stacey, Simone De Nobrega, Ardeshir Hakami, Harvey I. Pass, Berne Crawford, Jessica Donnington, Benjamin T. Cooper, Andre Moreirea, Audrey Sorensen, Leslie J. Kohman, Robert F. Dunton, Jason Wallen, Christopher Curtiss, Ernest M. Scalzetti, Linda Ellinwood, Clifford P. Connery, Emilo Torres, Dan Cruzer, Bruce Gendron, Sonya Alyea, Daniel J. Lackaye, Lauren Studer, Betsy Jane Becker, Artit Jirapatnakul, Nan You, Daniel M. Libby, James P. Smith, Mark Pasmantier, Anthony P. Reeves, Steven Markowitz, Albert Miller, José Cervera Deval, Heidi Roberts, Demetris Patsios, Shusuke Sone, Takaomi Hanaoka, Javier J. Zulueta, Juan P. de‐Torres, María D. Lozano, Ralph W. Aye, Kristin Manning, Christiana Care, Thomas W. Bauer, Stefano Canitano, Salvatore Giunta, Enser Cole, Karl Klingler, John H. M. Austin, Gregory D. Pearson, Dorith Shaham, Cheryl Aylesworth, Patrick Meyers, Shahriyour Andaz, Davood Vafai, David P. Naidich, Georgeann McGuinness, Barry Sheppard, Matthew D. Rifkin, M. Kristin Thorsen, Richard L. Hansen, Samuel Kopel, William Mayfield, Dan W. Luedke, Donald Klippenstein, Alan Litwin, Peter Loud, Richard J. Thurer, Nestor Villamizar, Arfa Khan, Rakesh Shah, Xueguo Liu, Gary Herzog, Diana Yeh, Ning Wu, J. Lowry, Mary Salvatore, Carmine Frumiento, David S. Mendelson, Michael V. Smith, Robert J. Korst, Jana Taylor, Michelle S. Ginsberg, Michaela Straznicka, Mark Widmann, G Cecchi, Terence A.S. Matalon, Paul Scheinberg, Shari-Lynn Odzer, David R. Olsen, Fred Grannis, Arnold Rotter, Daniel Ray, David Mullen, Peter H. Wiernik, Edson H. Cheung, Melissa Lim, Louis DeCunzo, Robert Glassberg, Carmen Endress, Mark Yoder, Palmi Shah, Laura S. Welch, Michael Kalafer, Jeremy Green, James J. Walsh, David Bertsch, Elmer Camacho, Cynthia Chin, James O’Brien, James C. Willey, Ning Wu

Bibliographic record

VenueJTCVS Open · 2022
Typearticle
Languageen
FieldMedicine
TopicLung Cancer Diagnosis and Treatment
Canadian institutionsnot available
FundersQueens College, City University of New YorkIrving Medical Center, Columbia UniversityBaylor University Medical CenterUniversity of TorontoBarbara Ann Karmanos Cancer InstituteUniversity of ToledoSt Joseph HospitalWeill Cornell Medical CollegeHadassah Medical OrganizationSimons Foundation
KeywordsMedicineHiatal herniaWedge resectionSurgeryLung cancerHerniaStage (stratigraphy)PneumonectomyLungCardiothoracic surgeryRadiologyResectionInternal medicineReflux

Abstract

fetched live from OpenAlex

Objective The study objective was to determine the relationship between lung resection and the development of postoperative hiatal hernia. Methods Preoperative and postoperative computed tomography imaging from 373 patients from the International Early Lung Cancer Action Program and the Initiative for Early Lung Cancer Research on Treatment were compared at a median of 31.1 months of follow-up after resection of clinical early-stage non–small cell lung cancer. Incidence of new hiatal hernia or changes to preexisting hernias were recorded and evaluated by patient demographics, surgical approach, extent of resection, and resection site. Results New hiatal hernias were seen in 9.6% of patients after lung resection (5.6% after wedge or segmentectomy and 12.4% after lobectomy; P = .047). The median size of new hernias was 21 mm, and the most commonly associated resection site was the left lower lobe (24.2%; P = .04). In patients with preexisting hernias, 53.5% demonstrated a small but significant increase in size from 21 to 22 mm ( P < .0001). All hernias persisted through the latest postoperative computed tomography scan. When 110 surgical patients without preexisting hernia were matched by sex, age, and smoking to nonoperative controls, the incidence of new hernia at follow-up was significantly higher among those who underwent surgery (17.3% vs 2.7%, P = .0003). Conclusions Both open and minimally invasive lung resection for clinical early-stage lung cancer are associated with new or enlarging postoperative hiatal hernia, especially after resections involving the left lower lobe.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.385
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2022
Admission routes1
Has abstractyes

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