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Effects of Vitamin D Levels on Cardiovascular Diseases: A SystematicReview

2022· review· en· W4214492933 on OpenAlex
Karoline de Macêdo Gonçalves Frota, Paulo Víctor de Lima Sousa, Larisse Monteles Nascimento, Amanda Ferreira Mesquita de Oliveira, Gleyson Moura dos Santos, Alana Rafaela da Silva Moura, Maísa Guimarães Silva Primo, Adriana de Azevedo Paiva, Betânia de Jesus e Silva de Almendra Freitas, Cecí­lia Maria Resende Gonçalves de Carvalho, Maria do Carmo de Carvalho e Martins

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCurrent Nutrition & Food Science · 2022
Typereview
Languageen
FieldMedicine
TopicVitamin D Research Studies
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineVitamin D and neurologyEpidemiologyCause of deathSystematic reviewInternal medicineScopusProspective cohort studyDiseasevitamin D deficiencyMEDLINEIntensive care medicine

Abstract

fetched live from OpenAlex

Background: Cardiovascular diseases (CVDs) are a group of pathologies that involve heart and blood vessel disorders and are considered the main cause of death in the world. Epidemiological studies have shown the association between low vitamin D (VD) levels and CVD. This vitamin, in addition to acting on bone metabolism, plays a role in modulating the cardiovascular system. Objective: The present study assesses the effects of VD levels on CVD through a systematic literature review. Method: For this purpose, the PICO strategy was used to prepare the guiding question, and articles were searched in the PubMed, Scopus, Science Direct, and Web of Science databases by two authors independently. To guarantee the quality of the evidence of the articles included in the review, the Newcastle-Ottawa scale was used. The literature review followed the PRISMA recommendations. Results: In this review, 22,757 articles were identified, but only 10 were considered eligible, of which 70 % are prospective cohorts and 30 % are retrospective cohorts. The study showed that low 25(OH)D levels correlate with an increased risk of cardiovascular events and death from CVD, including in patients who had preexisting CVD. However, one article did not demonstrate this association. Conclusion: As a result, VD correlates with cardiovascular events and the risk of death.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.731
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0040.002
Bibliometrics0.0010.003
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.125
GPT teacher head0.397
Teacher spread0.272 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it