MétaCan
Menu
Back to cohort
Record W4214650653 · doi:10.51887/jpfi.v10i2.1410

AKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN DAN BATANG SIDAGURI (Sida rhombifolia) TERHADAP MODEL HEWAN DIABETES TIPE 2

2021· article· id· W4214650653 on OpenAlexaff
Aulia Nurfazri Istiqomah, Widhya Aligita, Hendra Mahakam Putra, Denny Galang, Hapipah Nurjamilah

Bibliographic record

VenueJurnal Penelitian Farmasi Indonesia · 2021
Typearticle
Languageid
FieldMedicine
TopicNatural Antidiabetic Agents Studies
Canadian institutionsEncana (Canada)
Fundersnot available
KeywordsTraditional medicinePhysicsMedicine

Abstract

fetched live from OpenAlex

Diabetes merupakan penyakit yang ditandai dengan meningkatnya kadar glukosa dalam darah yang terjadi karena kurangnya produksi insulin atau berhentinya produksi insulin dalam tubuh. Herba Sidaguri (Sida rhombifolia) diketahui memiliki aktifitas sebagai antidiabetes. Penelitian ini dilakukan untuk mengevaluasi aktivitas antidiabetes ekstrak etanol daun dan batang sidaguri (Sida rhombifolia) terhadap model hewan diabetes tipe 2 dan mencari bagian mana yang paling efektif sebagai antidiabetes. Metode penelitian ini merupakan penelitian eksperimental secara in vivo. Mencit dibagi menjadi 9 Kelompok yaitu kelompok kontrol negative, kontrol positif, Glibenklamid 0,65 mg/KgBB, ekstrak daun sidaguri dosis 3,5; 7; dan 14 mg/KgBB, serta ekstrak batang sidaguri dosis 3,5; 7; dan 14 mg/KgBB. Pengujian dilakukan secara kuratif, hewan uji kecuali kontrol negatif, diberikan induksi aloksan monohidrat 80 mg/KgBB melalui rute intravena, kemudian setelah 3 hari pasca induksi, dilakukan pemeriksaan kadar glukosa darah puasa. Perlakuan dilanjutkan dengan pemberian terapi selama 14 hari melalui rute peroral. Parameter uji pada penelitian ini adalah pengukuran kadar glukosa daraah pada hari ke 0, 7, dan 14, serta histopatologi organ pancreas. Dari hasil pengujian diperoleh bahwa ekstrak yang memberikan efek antidiabetes terbaik adalah ekstrak etanol daun sidaguri dosis 14 mg/KgBB namun belum mampu memperbaiki kondisi sel-sel pankreas sepenuhnya.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.261
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

Explore more

Same venueJurnal Penelitian Farmasi IndonesiaSame topicNatural Antidiabetic Agents StudiesFrench-language works237,207