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Record W4221110796 · doi:10.5772/intechopen.102327

Molecular Epidemiology of High-Risk Human Papillomavirus Infection in Burkina Faso

2022· book-chapter· en· W4221110796 on OpenAlexaff
Théodora Mahoukèdè Zohoncon, Rogomenoma Alice Ouédraogo, Florencia Wendkuuni Djigma, Lassina Traore, Teega‐Wendé Clarisse Ouedraogo, Maïmouna Ilboudo, Régine Ilboudo, Catherine Salambanga, Sindimalgdé Patricia Guigma, S Tovo, Mah Alima Esther Traoré, Prosper Bado, Ali Kande, Cyrille Bisseyé, Abdoul Karim Ouattara, Ina Marie Angèle Traore, Djénèba Ouermi, Tani Sagna, Albert Théophane Yonli, Wendyam Marie Christelle Nadembega, Dorcas Obiri‐Yeboah, Yvette Marie Chantal Gyébré, Olga Mélanie Lompo, C.M.R. Ouédraogo, Jacques Simporè

Bibliographic record

VenueIntechOpen eBooks · 2022
Typebook-chapter
Languageen
FieldMedicine
TopicCervical Cancer and HPV Research
Canadian institutionsSt. Thomas University
Fundersnot available
KeywordsHuman papillomavirusGenotypeMedicineEpidemiologyHPV infectionCervical cancerGynecologyPopulationVirologyObstetricsInternal medicineBiologyCancerEnvironmental healthGeneticsGene

Abstract

fetched live from OpenAlex

The aim of the present study was to determine the distribution of high-risk human papillomavirus (HR-HPV) genotypes in childbearing age women, teenage girls, HIV-infected women, women with high-grade precancerous lesions and cervical cancer, sex workers, men, and otolaryngology tumor cases in Burkina Faso. This descriptive cross-sectional study with several target groups, consisted of 2386 samples from Burkina Faso. HR-HPV genotypes were characterized using real-time multiplex PCR. The prevalence of HR-HPV ranged from 15.63 to 72.31% depending on the target population and the nature of the samples. The most predominant genotypes in descending order were HPV-56, HPV-52, HPV-39, HPV-59, HPV-51, HPV-35, HPV-31, HPV-18, HPV-68, HPV-16, HPV-66, HPV-58, HPV-45, and HPV-33. The results of the present study show a wide variation in the distribution of HR-HPV genotypes in Burkina Faso. Genotypes 16 and 18 covered by HPV vaccines only accounted for 32.23% of HR-HPV cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.025

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.361
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

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