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Record W4224077382 · doi:10.53350/pjmhs22162938

Comparison of Nebulized vs Systemic Corticosteroids for Management of Children Presenting with Acute Exacerbation of Asthma

2022· article· en· W4224077382 on OpenAlexaff
Saima Gillani, Ghulam Abbas Qazi, Ibrahim, Samiullah Khan, Shazia Bibi, Abdul Hanan Farooq

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicInhalation and Respiratory Drug Delivery
Canadian institutionsAbbott (Canada)
Fundersnot available
KeywordsMedicineExacerbationAsthmaAsthma exacerbationsDemographicsPediatricsGroup BInhaled corticosteroidsInternal medicineDemography

Abstract

fetched live from OpenAlex

Objective: The aim of current study is to determine the outcomes of nebulized vs systemic corticosteroids for the treatment of children presenting with acute exacerbation asthma. Study Design: Simple blind/parallel study Place and Duration: Children Medical Center (CMC) / Dr Habib un Nabi Children Hospital Airport Road Mingora Swat and Pediatrics department of Ayub Medical College and Teaching Hospital, Abbottabad for the duration 06 months from April 2021 to September 2021. Methods: There were 60 cases of both genders presented with ages <10 years. Included patients had acute exacerbation of asthma. After obtaining written agreement, the demographics of all registered patients were recorded. Patients were split into 2-groups. Group I received nebulized corticosteroids and group II received systemic corticosteroids. Post treatment after 2 weeks of follow up outcomes among both groups were assessed by using oscillometric resistances. SPSS 21.0 version was used to analyze complete data. Results: There were 40 males (20 in each group) and 20 females (10 in each group). Mean age of the patients in group I was 5.8±7.45 years and group II had mean age 6.4±4.35 years. In group I 19 (63.3%) cases had family history of allergy and in group II 18 (60%) cases had history. Mean duration of asthma in group I was 3.4±6.15 years and in group II mean duration was 4.1±4.19 years. Mean hospitalization was lower in group I 1.5±3.14 days as compared to group II 2.8±9.31 days. By using oscillometric resistances reduction in disease severity was found higher in group I 4.1±5.14 as compared to group II 5.1±5.12 from 8.3±6.31. Conclusion: We concluded in this study that the use of nebulized steroids were effective and useful as compared to systemic steroid in the treatment of acute exacerbation asthma in terms of reduction of severity of disease and hospital stay.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.301
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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