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Vitamin D Focused Approach to Nutritional Therapy for the Managementof SARS-CoV-2 Pandemic: A Review

2022· review· en· W4224283693 on OpenAlexaff
Deepika Pawar, Anita Kumari, Rotimi E. Aluko, Ashwani Kumar

Bibliographic record

VenueCurrent Nutrition & Food Science · 2022
Typereview
Languageen
FieldMedicine
TopicVitamin D Research Studies
Canadian institutionsUniversity of Manitoba
Fundersnot available
KeywordsPandemicVitamin D and neurologyMedicineVitaminImmune systemImmunityIntensive care medicineMedical nutrition therapyCoronavirus disease 2019 (COVID-19)Intervention (counseling)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyInternal medicineInfectious disease (medical specialty)Disease

Abstract

fetched live from OpenAlex

Background: In several studies, Vitamin D supplementation was found useful against the highly infectious SARS-CoV-2 to reduce the mortality rate and severity of its infection. Viral replication was also found to be affected negatively by vitamin D administration. Objective: The literature was reviewed with an aim to evaluate the efficacy of the therapeutic approach of nutrition involving intervention of Vitamin D towards decreasing the severity of prevailing pandemic of SARS-CoV-2. Methods: A background research of literature was performed using the keywords “SARS-CoV- 2”, “Covid-19”, “nutritional therapy”, “Vitamin D”, “immunity”, “AEC2 receptors” and “RAS” in the Pubmed and Google Scholar. Results: This literature was review suggested that if combined with medical sciences, this nutritional therapy approach can end up as an influential solution to reduce the severity of SARSCoV- 2 infection, which is a prevailing pandemic. A combination of assessment, supplementation of this required micro-nutrient (Vitamin D), and monitoring can be used to aid the immune system of Covid-19 patients. Conclusion: Nutritional therapy with Vitamin D as a major factor can be used to increase the immunity of an individual to fight against the highly infectious SARS-CoV-2. However, the actual mechanism of how Vitamin D supplementation functions to improve the health of an individual is yet unclear.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.003
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.341
GPT teacher head0.463
Teacher spread0.122 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations2
Published2022
Admission routes1
Has abstractyes

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