The impact of eczema involving visible areas of the skin on patients' quality of life
Bibliographic record
Abstract
Abstract Rational Many studies have evaluated the impact of eczema according to the established severity. However, the specific impact of the location of eczema on the quality of life (QoL) has not been assessed. Objective In the present study, we focus on the burden of disease caused by the involvement of atopic dermatitis (AD) on visible areas of the face and hands. Methodology This study mobilized for each of the six countries where it was implemented (Canada, China, Italy, Spain, Germany and France), targeting a representative sample according to the quota method of their population aged 18 years and over. QoL was assessed through the QoL index (DLQI). Results We identified 801 people who reported having suffered exclusively from AD in the past 12 months. Overall, 31.7% ( n = 257) of the population considered their skin disease to be embarrassing with consequences in their personal life. Regarding stigmata, 15.7% ( n = 126) of people with eczema felt rejected, 15.5% ( n = 124) felt they were looked at with disgust and 33.1% ( n = 265) expressed a sense of discouragement. A significant impact was observed in 31.5% ( n = 145) of patients who had visible damage versus 12.3% ( n = 42) of patients with no visible damage ( p < 0.0001). The difference was also significant ( p < 0.001) when the average DLQI was assessed (6.6 vs. 4.8). Discussion The degradation of the QoL by AD is maximal when the hands and the face are affected simultaneously. The impact is also significantly higher when the hands are exclusively affected (compared to the face). The impact on the QoL is strongly linked to the experience and the lived experience of each patient, and the stigmata of the patients and their feelings of rejection are obvious. Surprisingly, exclusive hand involvement caused a higher impact in QoL than exclusive face involvement. Simultaneous involvement of the face and hands greatly amplifies the deterioration in QoL
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.080 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".