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Record W4225012768 · doi:10.1016/j.nicl.2022.103008

Excess significance and power miscalculations in neurofeedback research

2022· article· en· W4225012768 on OpenAlexfundno aff
Robert T. Thibault, Hugo Pedder

Bibliographic record

VenueNeuroImage Clinical · 2022
Typearticle
Languageen
FieldMedicine
TopicHeart Rate Variability and Autonomic Control
Canadian institutionsnot available
FundersFonds de Recherche du Québec - SantéUniversity of BristolNational Institute for Health and Care ResearchUniversity Hospitals Bristol NHS Foundation TrustLaura and John Arnold FoundationNational Institute on Handicapped Research
KeywordsStatistical powerNeurofeedbackFunctional magnetic resonance imagingPsychologyRepeated measures designStatistical hypothesis testingComputer scienceEconometricsStatisticsCognitive psychologyMathematicsElectroencephalographyNeuroscience

Abstract

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Recent systematic reviews of neurofeedback with functional magnetic resonance imaging (fMRI-nf) (Tursic et al., 2020) and neurofeedback with functional near infrared spectroscopy (fNIRS-nf) (Kohl et al., 2020) miscalculate the statistical power and statistical sensitivity of several studies they review.The fMRI-nf review overestimates the mean and median statistical power of included studies by about 3 times and the statistical sensitivity by about 2 times (see Table 1 for recalculated values and comparisons).The fNIRS-nf review, on which I (RTT) was a coauthor, overestimates power by about 2 times and sensitivity by about 1.5 times (see Table 2).The miscalculations arise from an easy-to-miss default option for repeated measures (mixed) 1 ANOVAs in the statistical software program GPower (Faul et al., 2007), which both reviews used (see Figure 1 for a depiction) 2 .The default option defines a variable in the effect size calculation η 2 p in such a way that the common usage of small, medium, and large effects sizes for the interaction of repeated measures (mixed) ANOVAs (f ) doesn't hold true.If unaware of the default option, the power calculations will account for the correlations between repeated measures a second time, and in turn substantially-but erroneously-increase power.The GPower software itself highlights that Cohen (1988) recommended another option (as viewable in Figure 1).While Lakens (2013) explained this issue almost 10 years ago, it remains likely that researchers continue to use GPower without awareness of this default option and its implications 3 .Fortunately, the authors of both reviews published their data as supplementary material, making reanalysis possible.We recalculated the statistical power and sensitivity of the studies from Tursic et al. ( 2020) and Kohl et al. 1 We use the term "repeated measures (mixed) ANOVA" to describe a study design with one independent measure and one repeated measure (e.g., two independent groups measured at two time points).GPower uses the term "ANOVA: Repeated measures" for this type of design.2 Kohl and coauthors (including me-RTT) were unaware of this default option in GPower.I was only led to become aware of this issue when reading the fMRI-nf review and noticing a surprising amount of statistical power.3 Kieslich (2020) provides a detailed explanation of how GPower calculates f for the different options for repeated measures (mixed) ANOVAs.The GPower team informed us that Cohen proposed Cohen's f for between-subjects designs and that this is how GPower defines f when using the default option, regardless of the ANOVA design the user selects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.126
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.178
GPT teacher head0.461
Teacher spread0.282 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2022
Admission routes1
Has abstractyes

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