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Record W4225287017 · doi:10.1007/s10620-022-07494-9

A Novel Decision Aid Improves Quality of Reproductive Decision-Making and Pregnancy Knowledge for Women with Inflammatory Bowel Disease

2022· article· en· W4225287017 on OpenAlexafffund
Grace Wang, Neda Karimi, Laura Willmann, Joseph L. Pipicella, Joseph Descallar, Katie O’Connor, Luiza Peculis, Yvette Leung, Susan J. Connor, Vivian Huang, Astrid‐Jane Williams

Bibliographic record

VenueDigestive Diseases and Sciences · 2022
Typearticle
Languageen
FieldMedicine
TopicPregnancy and Medication Impact
Canadian institutionsMount Sinai HospitalUniversity of British ColumbiaCanada Research ChairsUniversity of TorontoUniversity of New Brunswick
FundersGastroenterological Society of AustraliaUniversity of New South WalesWomen and Children's Health Research InstituteChildren's Health Research InstituteMerck
KeywordsMedicinePregnancyInflammatory bowel diseaseGynecologyUlcerative colitisObstetricsHepatologyDiseaseInternal medicineFamily medicine

Abstract

fetched live from OpenAlex

Abstract Background Women with inflammatory bowel disease (IBD) with poor IBD-specific reproductive knowledge experience more childlessness and fear of IBD medications in pregnancy. The Pregnancy in IBD Decision Aid (PIDA), developed by an international multidisciplinary team, offers personalized online decision support regarding pregnancy in IBD. Aims Assess the impact of PIDA on quality of reproductive decision-making and pregnancy-related knowledge among preconception (PC) and pregnant patients with IBD, and evaluate acceptability to patients and clinicians. Methods PC and pregnant patients with IBD aged 18–45 completed questionnaires pre- and post-PIDA to assess quality of decision-making (Decisional Conflict Scale (DCS); Decision Self-Efficacy Scale (DSES) and IBD-in-pregnancy knowledge (Crohn's and Colitis Pregnancy Knowledge Score (CCPKnow)). Paired t test assessed for differences pre- and post-PIDA. Patients and clinicians completed acceptability surveys. Results DCS and DSES were completed by 74 patients (42 Crohn’s disease, 32 ulcerative colitis); 41 PC and 33 pregnant. DCS improved significantly post-PIDA in PC patients regarding pregnancy planning ( t (40) = 4.83, p < 0.0001, Cohen’s d z = 0.75) and in pregnant patients regarding medication management ( t (32) = 2.37, p = 0.0242, d z = 0.41). DSES for PC patients improved significantly post-PIDA ( t (40) = -3.56, p = 0.001, d z = -0.56). CCPKnow improved significantly post-PIDA in PC ( t (42) = 4.93, p < 0.0001, d z = -0.75) and pregnant patients ( t (32) = 5.1, p < 0.0001, d z = -0.89). PIDA was deemed optimal for length, readability, and content amount and considered highly useful by patients ( n = 73) and clinicians ( n = 14). Conclusions Patients using PIDA developed an improved quality of reproductive decision-making and IBD-in-pregnancy knowledge. PIDA is an accessible tool that can empower women with IBD to make values-congruent, evidence-based decisions regarding pregnancy and may reduce voluntary childlessness.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.115
Threshold uncertainty score0.372

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.347
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2022
Admission routes2
Has abstractyes

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