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Record W4225319387

Reaching beyond maximum grade: progress and future directions for modernising the assessment and reporting of adverse events in haematological malignancies

2022· review· en· W4225319387 on OpenAlexaff
Gita Thanarajasingam, Lori M. Minasian, Vishal Bhatnagar, Franco Cavalli, R. Angelo de Claro, Amylou C. Dueck, Tarec Christoffer El‐Galaly, Neil Everest, Jan Geißler, Christian Gisselbrecht, Nicole Gormley, John G. Gribben, Mary M. Horowitz, S. Percy Ivy, Caron A. Jacobson, Armand Keating, Paul G. Kluetz, Yok‐Lam Kwong, Richard F. Little, Matthew J. Matasar, Kristen McCullough, Robert S. Miller, Mohamad Mohty, Philippe Moreau, Lindsay M. Morton, Sumimasa Nagai, Abhilasha Nair, Loretta J. Nastoupil, Kaye Robertson, Surbhi Sidana, Karin E. Smedby, Pieter Sonneveld, Kyriaki Tzogani, Flora E. van Leeuwen, Galina Velikova, Diego Villa, John R. Wingard, John F. Seymour, Thomas M. Habermann

Bibliographic record

VenueWhite Rose Research Online (University of Leeds, The University of Sheffield, University of York) · 2022
Typereview
Languageen
FieldMedicine
TopicCAR-T cell therapy research
Canadian institutionsPrincess Margaret Cancer CentreAstraZeneca (Canada)Spinal Cord Injury BCUniversity of British ColumbiaImmunovaccine (Canada)
Fundersnot available
KeywordsMedicineAdverse effectContext (archaeology)Intensive care medicineClinical trialCancerHematologyOncologyInternal medicine
DOInot available

Abstract

fetched live from OpenAlex

TEST 02 - Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.019
metaresearch head score (Gemma)0.025
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.981
Threshold uncertainty score0.098

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0190.025
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0040.004
Science and technology studies0.0010.002
Scholarly communication0.0040.007
Open science0.0030.002
Research integrity0.0030.008
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.162
GPT teacher head0.390
Teacher spread0.228 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations24
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueWhite Rose Research Online (University of Leeds, The University of Sheffield, University of York)Same topicCAR-T cell therapy researchFrench-language works237,207