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Record W4225379441 · doi:10.1016/j.envres.2022.113416

Relationships among green space, ambient fine particulate matter, and cancer incidence in Taiwan: A 16-year retrospective cohort study

2022· article· en· W4225379441 on OpenAlexfundno aff
Ying-Jhen Huang, Ping-Hsien Lee, Li-Chi Chen, Bo‐Cheng Lin, Changqing Lin, Ta‐Chien Chan

Bibliographic record

VenueEnvironmental Research · 2022
Typearticle
Languageen
FieldEnvironmental Science
TopicAir Quality and Health Impacts
Canadian institutionsnot available
FundersMinistry of Science and Technology, TaiwanHealth Research FoundationMinistry of Health and Welfare
KeywordsMedicineCancerHazard ratioBreast cancerIncidence (geometry)Proportional hazards modelRetrospective cohort studyCohortCohort studyLung cancerCancer registryProstate cancerInternal medicineEnvironmental healthConfidence interval

Abstract

fetched live from OpenAlex

Green space and air pollution have been recognized as vital health determinants. There is a paucity of studies examining the interplay between green space, fine particulate matter (PM2.5), and the incidence of specific cancers. We aimed to explore the contributions of green space and ambient PM2.5 to the risk of specific cancers in terms of the most common cancers based on incidence or mortality rate in Taiwan and to ascertain the interaction between green space and PM2.5 and their role in cancer risk. This retrospective longitudinal cohort study included 407,415 participants. Data were obtained from the 2000–2015 Mei Jau Health Examination Database linked to the Taiwan Cancer Registry and Causes of Death datasets. All participants were aged ≥20 years and had no history of cancer. The environmental exposure were the normalized difference vegetation index (NDVI) and the 2-year average PM2.5 at baseline. Multivariate adjusted hazard ratios (HRs) were calculated using Cox proportional hazards models. We adjusted for covariates including demographics, anthropometrics, comorbidities, health behaviors, biochemical data, and environmental factors. During a median follow-up of 10.37 years, 11,576 cancer cases were reported. PM2.5 exposure increased the risk of all cancers (HR: 1.11, [95% CI: 1.06–1.15]), stomach cancer (HR: 1.27, [1.02–1.58]), endocrine gland cancer (HR: 2.13, [1.39–3.26]), breast cancer (HR: 1.12, [1.03–1.22]), and lung cancer (HR: 1.12, [1.01–1.24]). An increase in NDVI reduced the risk of prostate cancer (HR: 0.93, [0.88–0.99]) and lung cancer (HR: 0.95, [0.91–0.99]). NDVI influenced the incidence of prostate and all cancers by reducing PM2.5 concentrations. Long-term PM2.5 exposure is associated with an increased risk of some types of cancers. In contrast, an increase in environmental green space exposure is associated with lowering of the risk of prostate and lung cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.987

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0140.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.069
GPT teacher head0.356
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations55
Published2022
Admission routes1
Has abstractyes

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