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Record W4226081232 · doi:10.1136/bmjopen-2021-054223

Identifying and addressing conflicting results across multiple discordant systematic reviews on the same question: protocol for a replication study of the Jadad algorithm

2022· article· en· W4226081232 on OpenAlexafffund
Carole Lunny, Sai Surabi Thirugnanasampanthar, Salmaan Kanji, Nicola Ferri, Pierre Thabet, Dawid Pieper, Sara Tasnim, Harrison Nelson, Emma K. Reid, Jia He Zhang, Banveer Kalkat, Yuan Chi, Jacqueline Thompson, Reema Abdoulrezzak, Di Wen Zheng, Lindy R.S. Pangka, Dian Wang, Parisa Safavi, Anmol Sooch, Kevin T. Kang, Sera Whitelaw, Andrea C. Tricco

Bibliographic record

VenueBMJ Open · 2022
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcGill UniversityMcGill University Health CentreNova Scotia Health AuthorityUniversity of British ColumbiaOttawa HospitalQueen's UniversityMontfort HospitalUniversity of OttawaUniversity of TorontoSt. Michael's Hospital
FundersOntario Ministry of Research and InnovationCanadian Institutes of Health Research
KeywordsMedicineReplication (statistics)Protocol (science)Jadad scaleSystematic reviewMEDLINEBioinformaticsAlgorithmAlternative medicinePathologyComputer science

Abstract

fetched live from OpenAlex

INTRODUCTION: An increasing growth of systematic reviews (SRs) presents notable challenges for decision-makers seeking to answer clinical questions. In 1997, an algorithm was created by Jadad to assess discordance in results across SRs on the same question. Our study aims to (1) replicate assessments done in a sample of studies using the Jadad algorithm to determine if the same SR would have been chosen, (2) evaluate the Jadad algorithm in terms of utility, efficiency and comprehensiveness, and (3) describe how authors address discordance in results across multiple SRs. METHODS AND ANALYSIS: We will use a database of 1218 overviews (2000-2020) created from a bibliometric study as the basis of our search for studies assessing discordance (called discordant reviews). This bibliometric study searched MEDLINE (Ovid), Epistemonikos and Cochrane Database of Systematic Reviews for overviews. We will include any study using Jadad (1997) or another method to assess discordance. The first 30 studies screened at the full-text stage by two independent reviewers will be included. We will replicate the authors' Jadad assessments. We will compare our outcomes qualitatively and evaluate the differences between our Jadad assessment of discordance and the authors' assessment. ETHICS AND DISSEMINATION: No ethics approval was required as no human subjects were involved. In addition to publishing in an open-access journal, we will disseminate evidence summaries through formal and informal conferences, academic websites, and across social media platforms. This is the first study to comprehensively evaluate and replicate Jadad algorithm assessments of discordance across multiple SRs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.259
metaresearch head score (Gemma)0.388
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad)
Consensus categoriesMetaresearch
DomainCandidate signal: Reproducibility · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.989
Threshold uncertainty score0.914

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2590.388
Meta-epidemiology (narrow)0.0070.006
Meta-epidemiology (broad)0.0110.017
Bibliometrics0.0140.013
Science and technology studies0.0060.009
Scholarly communication0.0080.011
Open science0.0050.007
Research integrity0.0130.011
Insufficient payload (model declined to judge)0.0370.012

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.912
GPT teacher head0.682
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designNot applicable
DomainReproducibility
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2022
Admission routes2
Has abstractyes

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