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Record W4229333208 · doi:10.2215/cjn.13191021

Multifaceted Intervention to Increase the Use of Home Dialysis

2022· article· en· W4229333208 on OpenAlexafffundabout
Braden Manns, Amit Garg, Manish M. Sood, Thomas W. Ferguson, S. Joseph Kim, David Naimark, Gihad Nesrallah, Steven Soroka, Monica Beaulieu, Stephanie N. Dixon, Ahsan Alam, Selina Allu, Navdeep Tangri

Bibliographic record

VenueClinical Journal of the American Society of Nephrology · 2022
Typearticle
Languageen
FieldMedicine
TopicDialysis and Renal Disease Management
Canadian institutionsSeven Oaks General HospitalUniversity of British ColumbiaDalhousie UniversityLibin Cardiovascular Institute of AlbertaOttawa HospitalHealth Sciences CentreSt. Michael's HospitalSunnybrook Health Science CentreWestern UniversityUniversity of TorontoUniversity of ManitobaUniversity of CalgaryMcGill University Health CentreInstitute for Clinical Evaluative SciencesUniversity of Ottawa
FundersCanadian Institutes of Health ResearchBaxter Healthcare CorporationKidney Foundation of CanadaResearch Manitoba
KeywordsMedicineDialysisHemodialysisHome hemodialysisRandomized controlled trialConfidence intervalIntervention (counseling)Peritoneal dialysisHome dialysisEmergency medicineCluster (spacecraft)Physical therapyInternal medicineNursing

Abstract

fetched live from OpenAlex

Background and objectives Home dialysis therapies (peritoneal and home hemodialysis) are less expensive and provide similar outcomes to in-center hemodialysis, but they are underutilized in most health systems. Given this, we designed a multifaceted intervention to increase the use of home dialysis. In this study, our objective was to evaluate the effect of this intervention on home dialysis use in CKD clinics across Canada. Design, setting, participants, & measurements We conducted a cluster randomized controlled trial in 55 CKD clinic clusters in nine provinces in Canada between October 2014 and November 2015. Participants included all adult patients who initiated dialysis in the year following the intervention. We evaluated the implementation of a four-component intervention, which included phone surveys from a knowledge translation broker, a 1-year center-specific audit/feedback on home dialysis use, delivery of an educational package (including tools aimed at both providers and patients), and an academic detailing visit. The primary outcome was the proportion of patients using home dialysis at 180 days after dialysis initiation. Results A total of 55 clinics were randomized (27 in the intervention and 28 in the control), with 5312 patients initiating dialysis in the 1-year follow-up period. In the primary analysis, there was no difference in the use of home dialysis at 180 days in the intervention and control clusters (absolute risk difference, 4%; 95% confidence interval, −2% to 10%). Using a difference-in-difference comparison, the use of home dialysis at 180 days was similar before and after implementation of the intervention (difference of 0% in intervention clinics; 95% confidence interval, −2% to 3%; difference of 0.8% in control clinics; 95% confidence interval, −1% to 3%; P =0.84). Conclusions A multifaceted intervention did not increase the use of home dialysis in adults initiating dialysis. Clinical Trial registry name and registration number: A Cluster Randomized Trial to Assess the Impact of Patient and Provider Education on Use of Home Dialysis, NCT02202018

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.087

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.362
Teacher spread0.297 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2022
Admission routes3
Has abstractyes

Explore more

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