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Record W4229445525 · doi:10.21203/rs.3.rs-1614891/v1

Validation of the Self-Reported Domains of the Edmonton Frail Scale in Patients 65 Years of Age and Older

2022· preprint· en· W4229445525 on OpenAlexaboutno aff
Luxey Sirisegaram, Oluwafemi P. Owodunni, April L. Ehrlich, Caroline X. Qin, Dianne Bettick, Susan L. Gearhart

Bibliographic record

VenueResearch Square · 2022
Typepreprint
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsReceiver operating characteristicMedicineObservational studySpecialtyGerontologyPhysical therapyInternal medicineFamily medicine

Abstract

fetched live from OpenAlex

Abstract Introduction: In the era of virtual care, self-reported tools are beneficial for preoperative assessments and facilitating postoperative planning. We have previously reported the use of the Edmonton Frailty Scale (EFS) as a valid preoperative assessment tool. Objective: We wished to validate the self-reported domains of the EFS (srEFS) by examining its association with loss of independence (LOI) and mortality. Methods: This is a single-institution observational study of patients ≥ 65 years undergoing multi-specialty surgical procedures who were assessed preoperatively with the EFS. Exploratory data analysis of the EFS was used to determine the threshold for identifying frailty on the srEFS. Procedures were classified using the Operative Stress Score (OSS) scored 1 – 5 (lowest to highest). Hierarchical Condition Category (HCC) was utilized to risk-adjust. LOI was described as a change in functional status at discharge and mortality was defined as in-hospital or up to 30 days following discharge. Receiver operating characteristic (ROC) curves were used to estimate areas under the curves for srEFS versus EFS in relation to LOI and 30-day mortality. Results: 535 patients were included. Exploratory analysis confirmed best positive predictive value for srEFS was ³5. Overall, 113 (21%) patients were frail and 179 (33.5%) patients had an 0SS ³5. LOI occurred in 38 (7%) patients and the mortality rate was 4% (21 patients). ROC analysis showed that the srEFS performed similarly the standard EFS with no difference in discriminatory thresholds for predicting LOI and mortality. Examination of the domains of the EFS demonstrated a lack of association between cognitive decline and the outcomes of interest. However, functional status assessed with either the Get up and Go or self-reported ADLs was independently associated with increased risk for LOI.Conclusion: This study shows that self-reported components EFS are sufficiently valid as a high-risk assessment and are useful in virtual preoperative evaluation to help predict LOI and mortality.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.348
Teacher spread0.318 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2022
Admission routes1
Has abstractyes

Explore more

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