Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Post-publication record
OpenAlex flags this work as retracted, but it carries no matching Retraction Watch record in this frame.
Abstract
Introduction: Elocta is an Fc Fusion Protein classified as an extended half-life (EHL) drug for the management of patients with Haemophilia A. Several different laboratory assay methods can be used to monitor Elocta in patient plasma samples. Methods: In a supplementary UK NEQAS BC exercise 4 lyophilised samples containing Elocta were distributed to 81 participating centres. Sample S19:02 was from a patient with severe Haemophilia A treated with Elocta, but prior to sample collection was at a treatment trough level. S19:03 was from a patient with severe Haemophilia A patient, treated with 2000 iu/kg Elocta 15 minutes prior to sample collection. Samples S19:04 and S19.05 were constructed by 'spiking' FVIII deficient plasma, from a severe haemophilia A donor, with Elocta-Sample S19.04 at a level similar to a patient trough level and Sample S19:05 at a level similar to a patient post treatment level. Participants were invited to perform a FVIII assay on each of the four samples using testing methods in regular routine use in their laboratory.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Haemophilia
- Topic
- Hemophilia Treatment and Research
- Field
- Medicine
- Canadian institutions
- —
- Funders
- Chugai PharmaceuticalLEO PharmaGrifolsUniversidade Estadual de MaringáAlexion PharmaceuticalsUniversitat de ValènciaUniversidade Estadual de LondrinaLeids Universitair Medisch CentrumSwedish Orphan BiovitrumNovo NordiskChristian Medical College, VelloreUniversity of OxfordImperial College Healthcare NHS TrustUniversity of WashingtonImperial College LondonRoyal Free London NHS Foundation TrustBarts Health NHS TrustGreat Ormond Street Hospital for ChildrenSt Mary's UniversityKing's College LondonMcMaster UniversityUniversity of ChesterCSL BehringSanofiUniversidade Federal de Minas GeraisHospital for Sick ChildrenPfizerUniversitair Medisch Centrum UtrechtAmgen
- Keywords
- Medicine
- Has abstract in OpenAlex
- yes