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Record W4231078373 · doi:10.31979/etd.c8tt-5feh

Identifying Predictors of Airway Complications in Conscious Sedation Procedures

2019· dissertation· en· W4231078373 on OpenAlexaboutno aff
Rosemary Bray

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldMedicine
TopicObstructive Sleep Apnea Research
Canadian institutionsnot available
Fundersnot available
KeywordsSedationMedicineAirwayAirway obstructionObstructive sleep apneaAnesthesiaIntensive care medicineVerifiable secret sharingSleep apneaComputer science

Abstract

fetched live from OpenAlex

Problem: Conscious sedation procedures are complicated by unanticipated airway compromise and obstruction. The STOP-Bang questionnaire (University of Toronto, 2012) is a validated obstructive sleep apnea (OSA) screening questionnaire used as a pre-procedure evaluation tool to assess a patient’s risk for OSA. There are four verifiable, objective questions and four subjective questions. This study examines to what extent the STOP-Bang score question variables reliably predict airway complications during conscious sedation procedures. Method: The method was a retrospective review of data from the electronic medical record (EMR) of patients who had conscious sedation for endoscopy procedures. The individual questions of the STOP-Bang questionnaire were manually collected as independent predictor variables. Physiologic signs of airway compromise and documented airway maneuvers to relieve airway obstruction were collected as dependent outcome variables. Logistic regression analysis was preformed to predict outcome severity based on individual and total STOP-Bang questionnaire scores. Results: A STOP-Bang threshold score of greater than 5, indicating a high risk for OSA, was determined to be predictive of a heart rate change greater than 10% from baseline during the procedure (p =.021) and periods of apnea of (respiratory rate less than or equal to 8 seconds) (p = .038), indicating airway compromise. The STOP-Bang threshold score of greater than 5 was statistically significantly when correlated to the patient requiring arousal-relieved airway obstruction by verbal or tactile stimulation (p = .023). For the predictor variable of every point of increase in Body Mass Index (BMI), there was a statistically significant correlation with an increase in heart rate during the procedure by 10%, (p = .046), a drop in oxygen saturation as measured by pulse oximetry (SpO2) (p = .002), and periods of apnea (respiratory rate less than or equal to 8) (p = .003). Additionally, for every point of increase in BMI there was 1.212 times the odds of requiring verbal or tactile stimulation to relieve airway obstruction (p = .002). The predictor variable of an STOP-Bang score between 3 and 4, indicating intermediate risk for OSA, was correlated to the development of abnormal CO2 values during the procedure (p = 0.15). Conclusion: With these findings, proactive safety measures can be instituted for additional airway management for identified at-risk patients. This information has application in the clinical consideration of monitoring protocols, medication administration, equipment availability, and staffing for patients with a high probability for airway obstruction during conscious sedation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.350
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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