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Skeletal Muscle Metabolic and Performance Adaptations After Short Sprint Interval Training (SIT).

2004· article· en· W4231257321 on OpenAlexaffabout
Kirsten A. Burgomaster, George J. F. Heigenhauser, Martin J. Gibala

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsMcMaster University
Fundersnot available
KeywordsSprintInterval trainingMedicineTime trialCycle ergometerPhysical therapyWingate testExercise physiologyAnaerobic exerciseHeart rateInternal medicineBlood pressure

Abstract

fetched live from OpenAlex

0152 Recent work by our group showed that 6 bouts of SIT over 2 wks dramatically improved cycle endurance capacity, such that mean time to exhaustion increased from ∼25 to 51 min during exercise at 80%VO2peak (Hughes et al., Med. Sci. Sports Exerc., 35:S337, 2003). PURPOSE: We examined the effect of SIT on: (1) skeletal muscle metabolic adaptations during an incremental cycle exercise Challenge Ride (CR); and (2) since many events require athletes to complete a fixed amount of work in as short a time as possible (i.e., a race), we assessed changes in Time Trial (TT) performance. METHODS: 8 recreationally active men (21.1±0.5 yr) performed 6 sessions of SIT (6 bouts × 4–7 “all out” 30-sec Wingate tests, separated by 4 min of recovery) over a 2 wk period. Before and 2–3 d following the SIT protocol, subjects completed (1) a CR that consisted of 10 min @ 50% followed by 10 min @ 80%VO2peak, and biopsies were obtained at rest and after each workload; and (2) a 250 kJ selfpaced TT on a cycle ergometer with no temporal, verbal or physiological feedback. Extensive familiarization trials were performed prior to the study, and method error reproducibility (CV) for the TT was 5.5% when subjects were tested 1 wk apart with no SIT intervention (Day 1: 16.8±2.1 vs Day 2: 17.1±1.4 min). RESULTS: The maximal activity of citrate synthase was 18% higher after SIT (Post: 11.8 ± 0.4 vs Pre: 10.0 ± 0.8 mmol·kg−1·min−1 wet wt., P<0.05). Resting muscle [glycogen] increased by 53% after SIT (Post: 377±21 vs Pre: 247±14 mmol·kg−1 dry wt., P<0.05). Net muscle glycogenolysis was lower during the CR after SIT, and muscle [lactate] was reduced after 10 and 20 min of exercise (P<0.05). TT performance improved by 10.4% (Post: 15.3±1.5 vs Pre: 17.3±2.7 min) and average power increased from 247±37 to 272±24 W (both P<0.05). CONCLUSION: 6 sessions of SIT performed over 2 wks (∼15 min total exercise time) increased muscle oxidative capacity and altered muscle glycogen metabolism during exercise in recreationally active young men. SIT appeared to decrease reliance on non-oxidative energy metabolism during cycling at a given absolute load (CR), and decreased the time required to complete a fixed amount of work (TT). Supported by NSERC Canada, an ACSM Research Endowment Grant, and a Gatorade Sports Science Institute Student Research Award (KAB).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.260
Teacher spread0.245 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2004
Admission routes2
Has abstractyes

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