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P-001 Permanent Implantation of the Solitaire Device as a Bailout Technique for Large Vessel Intracranial Occlusions

2016· article· en· W4231267726 on OpenAlexaff
J Houde, E Barber, M Kelly, L Peeling

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsSolitaire Cryptographic AlgorithmMedicineThrombusStroke (engine)SurgeryStentOcclusionRadiologyCardiologyIschemic strokeIschemiaModified Rankin Scale

Abstract

fetched live from OpenAlex

Introduction The Solitaire (Medtronic, Minneapolis, MN) is a stentriever device for endovascular treatment of acute ischemic stroke (AIS). The Solitaire is well described for use in temporary endovascular bypass, and mechanical thrombectomy. Permanent placement of the Solitaire is an option, but there are limited reports to date. The authors of this study review six cases of Solitaire stent implantation in the setting of large vessel occlusion and acute ischemic stroke, where temporary endovascular bypass and mechanical thrombectomy failed. Materials and methods Six cases of failed mechanical thrombectomy are reviewed, including procedural review, timing of anti-platelet agents, and radiographic and clinical outcomes. Results Six patients with severe, acute ischemic stroke (AIS) and large vessel occlusion (LVO) were triaged to mechanical thrombectomy. Despite multiple attempts at mechanical thrombus retrieval with a combination of devices including stentrievers and direct thrombus aspiration, flow could not be restored. As a bailout maneuver, the Solitaire stent was deployed and detached across the thrombus with TICI grade 3 flow restoration. All patients were loaded with full dose intra-arterial abciximab immediately after stent deployment and transitioned to dual antiplatelet therapy within 24 hours. There were no post-procedure hemorrhagic complications. All patients had significant neurological improvement post-procedurally, with favorable modified Rankin scores at follow-up. Conclusion With the recent over-whelming evidence demonstrating the effectiveness endovascular therapy in acute ischemic stroke, the expansion of stroke therapy requires that a variety of techniques be available to the operators. Permanent implantation of the Solitaire stent achieves adequate distal flow and good clinical outcomes in the setting of AIS. This case series suggests this technique provides a safe alternative for difficult cases refractory to other revascularization techniques. Key Words stroke, revascularization, stent Disclosures J. Houde: None. E. Barber: None. M. Kelly: 2; C; Medtronic. 4; C; Blockade. 6; C; Penumbra. L. Peeling: None.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.287
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2016
Admission routes1
Has abstractyes

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