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Record W4231601834 · doi:10.1093/pch/11.6.332a

The authors respond

2006· article· en· W4231601834 on OpenAlexaffabout
C Robin Walker, Richard H. van der Jagt, Paul Claman

Bibliographic record

VenuePaediatrics & Child Health · 2006
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPesticide Exposure and Toxicity
Canadian institutionsOttawa HospitalChildren's Hospital of Eastern OntarioUniversity of Ottawa
Fundersnot available
KeywordsMedicineComputer scienceIntensive care medicine

Abstract

fetched live from OpenAlex

In response to our article “Pesticide assessment: Protecting public health on the home turf”, the Industry Task Force II on 2,4-D Research Data asserts that Canada's risk assessment led to “incredible (sic) confidence … that 2,4-D does not pose a risk to human health.” To put this opinion in perspective, the Task Force consortium owns the registrations for the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), and funds and circulates research studies to government agencies, including to Canada's Pest Management Regulatory Agency (PMRA). The Task Force contends that 2,4-D does not pose a cancer risk, but Canada's and other cited government agencies found that the evidence was inconclusive. This is not the same as risk-free. Recent writings of Gandhi and Alavanja (1,2), authors cited by the Task Force, also diverge from the risk-free message. Gandhi published a fact sheet indicating that 2,4-D may be linked to breast cancer via mechanisms other than mutagenesis, such as hormonal effects. Indeed, 2,4-D exhibits estrogenic and androgenic effects in vitro. Endocrine effects were not considered in the 2,4-D reassessment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.415
Threshold uncertainty score0.862

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.238
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes2
Has abstractyes

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